Novel lipid-coated magnetic nanoparticles for in vivo imaging

Huey Chung Huang, Po Yuan Chang, Karen Chang, Chao Yu Chen, Chung Wu Lin, Jyh Horng Chen, Chung Yuan Mou, Zee Fen Chang, Fu Hsiung Chang

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Application of superparamagnetic iron oxide nanoparticles (SPIOs) as the contrast agent has improved the quality of magnetic resonance (MR) imaging. Low efficiency of loading the commercially available iron oxide nanoparticles into cells and the cytotoxicity of previously formulated complexes limit their usage as the image probe. Here, we formulated new cationic lipid nanoparticles containing SPIOs feasible for in vivo imaging.

Original languageEnglish
Title of host publicationRecent Advances in Nanotechnology
PublisherApple Academic Press
Pages43-54
Number of pages12
ISBN (Electronic)9781466558465
ISBN (Print)9781926692739
Publication statusPublished - Jan 1 2011
Externally publishedYes

Keywords

  • Dulbecco’s modified eagle’s medium
  • Human cervical cancer cells
  • Magnetic resonance
  • Polyethylene glycol
  • Superparamagnetic iron oxide nanoparticles

ASJC Scopus subject areas

  • General Chemistry
  • General Engineering

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