Normal Pressure Hydrocephalus Mimicking Antipsychotic-induced Parkinsonism

Ting-Jen Cheng, Wen Chen Ouyang, Mei-Chih Tseng, Ming Been Lee, His-Chung Chen

Research output: Contribution to journalArticlepeer-review


Objective: Normal pressure hydrocephalus (NPH) is a diagnostic challenge for clinicians due to significant variations in its clinical presentation, especially in patients with a psychiatric history. Case Report: A 47-year-old female with chronic schizophrenia had extrapyramidal symptoms (EPS) while being admitted on the psychiatric ward. Her EPS were initially considered to be induced by antipsychotic drugs, but the symptoms persisted despite adjustments in medication. The finding of the computed tomographic scan later revealed NPH. After being implanted a ventriculo-peritoneal shunt, her EPS were gradually improved. Conclusion: The typical symptoms of NPH are similar to some of the common mental disorders, or the side effects induced by antipsychotic drugs. NPH is suggested to be considered when schizophrenic patients are presenting a gait or movement disturbance but with poor response to the management for EPS.
Original languageEnglish
Pages (from-to)167-171
JournalTaiwanese Journal of Psychiatry (Taipei)
Issue number2
Publication statusPublished - Jun 1 2009

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