Natural Coumarin Derivative Esculetin Regulates Platelet Activation via Modulating NF-κB Signaling in Cyclic Nucleotide-Independent Manner

Agriculture & Biology

• platelet activation 85%
• vasodilator agents 72%
• coumarin 71%
• phosphoproteins 71%
• cyclic nucleotides 69%
• phosphorylation 52%
• integrins 49%
• chemical derivatives 45%
• collagen 34%
• nitroglycerin 27%
• elastase 24%
• isothiocyanates 23%
• phospholipase C 22%
• fluorescein 22%
• fibrinogen 22%
• protein kinase C 22%
• hydroxyl radicals 21%
• B-lymphocytes 19%
• prostaglandins 18%
• animal models 17%
• bioactive properties 17%
• degradation 12%
• cells 6%

Medicine & Life Sciences

• esculetin 100%
• Coumarins 83%
• Cyclic Nucleotides 71%
• Platelet Activation 65%
• vasodilator-stimulated phosphoprotein 39%
• Blood Platelets 33%
• Phosphorylation 17%
• Integrins 16%
• Collagen 12%
• isothiocyanic acid 10%
• Pancreatic Elastase 10%
• Alprostadil 10%
• Nitroglycerin 9%
• Type C Phospholipases 9%
• Hydroxyl Radical 9%
• Fluorescein 9%
• Fibrinogen 8%
• Protein Kinase C 8%
• B-Lymphocytes 6%
• Animal Models 6%
• Light 6%

Chemical Compounds

• Esculetin 96%
• Coumarin 62%
• Anticoagulant Agent 25%
• Prostaglandin E1 14%
• Nitroglycerin 14%
• Cyclic Nucleotide 13%
• Fluorescein 10%
• Collagen 9%
• Bioactivity 7%
• Protein 4%