National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

Po Yu Liu, Yu Lin Lee, Min Chi Lu, Pei Lan Shao, Po Liang Lu, Yen Hsu Chen, Shu Hsing Cheng, Wen Chien Ko, Chi Ying Lin, Ting Shu Wu, Muh Yong Yen, Lih Shinn Wang, Chang Pan Liu, Wen Sen Lee, Yao Shen Chen, Fu Der Wang, Shu Hui Tseng, Chao Nan Lin, Hung Jen Tang, Yu Hui ChenWang Huei Sheng, Chun Ming Lee, Ming Huei Liao, Po Ren Hsueh

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

A multicenter collection of bacteremic isolates of Escherichia coli (n = 423), Klebsiella pneumoniae (n = 372), Pseudomonas aeruginosa (n = 300), and Acinetobacter baumannii complex (n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae (n = 28) and one (20%) carbapenem-resistant E. coli (n = 5) isolate harbored blaKPC (n = 17), blaOXA-48 (n = 2), and blaVIM (n = 1) genes.

Original languageEnglish
Article numbere01089
JournalAntimicrobial Agents and Chemotherapy
Volume64
Issue number10
DOIs
Publication statusPublished - Sept 21 2020

Keywords

  • carbapenemases
  • colistin
  • Enterobacteriaceae
  • KPC
  • mcr-1

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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