TY - JOUR
T1 - Nasopharyngeal carcinoma with pericardial metastasis
AU - Chen, Shang Wen
AU - Chen, Chao Hsun
AU - Tsao, Chao Jung
AU - Huang, Wen Tsung
AU - Chuang, Shih Sung
PY - 2011/7
Y1 - 2011/7
N2 - Nasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with dyspnea and orthopnea. Serial studies, including pericardial biopsy, revealed NPC with pericardial metastasis and pericardial effusion. The tumor cells of both the original and metastatic tumors were positive for Epstein-Barr virus by in situ hybridization. This is the first histologically confirmed case of NPC with pericardial metastasis.
AB - Nasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with dyspnea and orthopnea. Serial studies, including pericardial biopsy, revealed NPC with pericardial metastasis and pericardial effusion. The tumor cells of both the original and metastatic tumors were positive for Epstein-Barr virus by in situ hybridization. This is the first histologically confirmed case of NPC with pericardial metastasis.
KW - Epstein-Barr virus
KW - Nasopharyngeal carcinoma
KW - Pericardium
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U2 - 10.1016/j.kjms.2010.08.005
DO - 10.1016/j.kjms.2010.08.005
M3 - Article
C2 - 21757147
AN - SCOPUS:79960373697
SN - 1607-551X
VL - 27
SP - 289
EP - 291
JO - Kaohsiung Journal of Medical Sciences
JF - Kaohsiung Journal of Medical Sciences
IS - 7
ER -