Nasopharyngeal carcinoma with pericardial metastasis

Shang Wen Chen, Chao Hsun Chen, Chao Jung Tsao, Wen Tsung Huang, Shih Sung Chuang

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3 Citations (Scopus)


Nasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with dyspnea and orthopnea. Serial studies, including pericardial biopsy, revealed NPC with pericardial metastasis and pericardial effusion. The tumor cells of both the original and metastatic tumors were positive for Epstein-Barr virus by in situ hybridization. This is the first histologically confirmed case of NPC with pericardial metastasis.

Original languageEnglish
Pages (from-to)289-291
Number of pages3
JournalKaohsiung Journal of Medical Sciences
Issue number7
Publication statusPublished - Jul 2011


  • Epstein-Barr virus
  • Nasopharyngeal carcinoma
  • Pericardium

ASJC Scopus subject areas

  • Medicine(all)


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