Nasal NK/T-cell lymphoma with cutaneous involvement

Zheng Ping Shi, Chien Yu Pai, Hsing Won Wang

Research output: Contribution to journalArticlepeer-review


The immunophenotype of nasal natural killer (NK)/T-cell lymphoma is characterized as CD56+ and cytoplasmic CD3 (CD3ε)+, but is usually surface CD3-. Most patients with this lymphoma present with lesions in the nasal region and sometimes secondary spreading. Patients rarely present with a lesion located primarily in the skin or soft tissue and relapse in the nose. We report on a 49-year-old woman who presented initially with progressive cutaneous lesions over 6 months. Nasal obstruction and nasal discharge appeared for about 1 month. We examined a mass from the left inferior turbinate and performed biopsies of the nasal and cutaneous lesions to confirm the nasal NK/T-cell lymphoma with cutaneous involvement. She received concurrent chemoradiotherapy. Clinicians should consider the possibility of nasal NK/T-cell lymphoma if the diseased nasal condition progresses; the nasal region should be examined in detail when NK/T-cell lymphoma is found in an extranasal site.

Original languageEnglish
Pages (from-to)243-246
Number of pages4
JournalJournal of Medical Sciences
Issue number5
Publication statusPublished - Oct 2005
Externally publishedYes


  • Angiocentricity
  • Nasal NK/T-cell lymphoma
  • Primary nasal lymphoma

ASJC Scopus subject areas

  • General Medicine


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