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N-Methylpropargylamine-Conjugated Hydroxamic Acids as Dual Inhibitors of Monoamine Oxidase A and Histone Deacetylase for Glioma Treatment
Samir Mehndiratta
, Bin Qian
,
Jian Ying Chuang
,
Jing Ping Liou
, Jean C. Shih
Ph.D. Program in Medical Neuroscience
TMU Research Center of Drug Discovery
School of Pharmacy
International Master Program in Medical Neuroscience
Ph.D. Program in Drug Discovery and Development Industry
Research output
:
Contribution to journal
›
Article
›
peer-review
20
Citations (Scopus)
Overview
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Dive into the research topics of 'N-Methylpropargylamine-Conjugated Hydroxamic Acids as Dual Inhibitors of Monoamine Oxidase A and Histone Deacetylase for Glioma Treatment'. Together they form a unique fingerprint.
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Medicine and Dentistry
Ganglioglioma
100%
Hydroxamic Acid
100%
Amine Oxidase (Flavin Containing) Isoenzyme A
100%
Histone Deacetylase
100%
Neoplasm
33%
Monoamine Oxidase A Inhibitor
33%
IC50
33%
Survival Rate
16%
Cancer
16%
Cell Death
16%
Cell Growth
16%
Tubulin
16%
Translational Research
16%
Acetylation
16%
Histone H3
16%
Pharmacology, Toxicology and Pharmaceutical Science
Hydroxamic Acid
100%
Amine Oxidase (Flavin Containing) Isoenzyme A
100%
Histone Deacetylase
100%
Monoamine Oxidase A Inhibitor
33%
Neoplasm
33%
IC50
33%
Survival Rate
16%
Tubulin
16%
Histone H3
16%
Biochemistry, Genetics and Molecular Biology
Histone Deacetylase
100%
Monoamine Oxidase A
100%
IC50
25%
Acetylation
12%
Isoform
12%
Survival Rate
12%
Tubulin
12%
Tumor Volume
12%
Cell Death
12%
Cell Growth
12%
Histone H3
12%