Myeloblastic leukemoid reaction in paroxysmal nocturnal hemoglobinuria associated with myelodysplasia

W. S. Ko; L. M. Chen; T. Y. Chao; W. S. Hwang

doi:10.1159/000204721

Myeloblastic leukemoid reaction in paroxysmal nocturnal hemoglobinuria associated with myelodysplasia

W. S. Ko, L. M. Chen, T. Y. Chao, W. S. Hwang

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Paroxysmal nocturnal hemoglobinuria (PNH) has been observed to evolve into myelofibrosis and acute myeloid leukemia. Myeloblastic leukemoid reaction has not been described in PNH. We described a patient with PNH with myelodysplasia and septicemia. The marrow aspirates showed a picture of myeloblastosis which subsided when sepsis was controlled. The myeloblastic leukemoid reaction in our patient related to overwhelming sepsis, splenectomy and overt hemolysis.

Original language	English
Pages (from-to)	75-77
Number of pages	3
Journal	Acta Haematologica
Volume	87
Issue number	1-2
DOIs	https://doi.org/10.1159/000204721
Publication status	Published - 1992
Externally published	Yes

Keywords

Myeloblastic leukemoid reaction
Paroxysmal nocturnal hemoglobinuria

ASJC Scopus subject areas

Hematology

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10.1159/000204721

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title = "Myeloblastic leukemoid reaction in paroxysmal nocturnal hemoglobinuria associated with myelodysplasia",

abstract = "Paroxysmal nocturnal hemoglobinuria (PNH) has been observed to evolve into myelofibrosis and acute myeloid leukemia. Myeloblastic leukemoid reaction has not been described in PNH. We described a patient with PNH with myelodysplasia and septicemia. The marrow aspirates showed a picture of myeloblastosis which subsided when sepsis was controlled. The myeloblastic leukemoid reaction in our patient related to overwhelming sepsis, splenectomy and overt hemolysis.",

keywords = "Myeloblastic leukemoid reaction, Paroxysmal nocturnal hemoglobinuria",

author = "Ko, {W. S.} and Chen, {L. M.} and Chao, {T. Y.} and Hwang, {W. S.}",

year = "1992",

doi = "10.1159/000204721",

language = "English",

volume = "87",

pages = "75--77",

journal = "Acta Haematologica",

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T1 - Myeloblastic leukemoid reaction in paroxysmal nocturnal hemoglobinuria associated with myelodysplasia

AU - Ko, W. S.

AU - Chen, L. M.

AU - Chao, T. Y.

AU - Hwang, W. S.

PY - 1992

Y1 - 1992

N2 - Paroxysmal nocturnal hemoglobinuria (PNH) has been observed to evolve into myelofibrosis and acute myeloid leukemia. Myeloblastic leukemoid reaction has not been described in PNH. We described a patient with PNH with myelodysplasia and septicemia. The marrow aspirates showed a picture of myeloblastosis which subsided when sepsis was controlled. The myeloblastic leukemoid reaction in our patient related to overwhelming sepsis, splenectomy and overt hemolysis.

AB - Paroxysmal nocturnal hemoglobinuria (PNH) has been observed to evolve into myelofibrosis and acute myeloid leukemia. Myeloblastic leukemoid reaction has not been described in PNH. We described a patient with PNH with myelodysplasia and septicemia. The marrow aspirates showed a picture of myeloblastosis which subsided when sepsis was controlled. The myeloblastic leukemoid reaction in our patient related to overwhelming sepsis, splenectomy and overt hemolysis.

KW - Myeloblastic leukemoid reaction

KW - Paroxysmal nocturnal hemoglobinuria

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VL - 87

SP - 75

EP - 77

JO - Acta Haematologica

JF - Acta Haematologica

IS - 1-2

ER -

Myeloblastic leukemoid reaction in paroxysmal nocturnal hemoglobinuria associated with myelodysplasia

Abstract

Keywords

ASJC Scopus subject areas

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