TY - JOUR
T1 - Mycobacterium tuberculosis infection of end-stage renal disease patients in Taiwan
T2 - A nationwide longitudinal study
AU - Li, S. Y.
AU - Chen, T. J.
AU - Chung, K. W.
AU - Tsai, L. W.
AU - Yang, W. C.
AU - Chen, J. Y.
AU - Chen, T. W.
PY - 2011/11
Y1 - 2011/11
N2 - End-stage renal disease (ESRD) patients are vulnerable to Mycobacterium tuberculosis (MTB) infection, but the magnitude of the risk is uncertain. In addition, there is no reliable information on the MTB infection rate of patients undergoing different types of renal replacement therapy (RRT). We used the Taiwan National Health Insurance Research Database to conduct a 9-year nationwide longitudinal study. Among 49983 ESRD patients who received three renal replacement modalities, there were 562 cases of MTB infection, corresponding to an incidence rate of 3.0 per 1000 patient-years. The risk of MTB infection relative to the general population was 4.5. Multivariate Cox regression analysis indicated that the independent risk factors for MTB infection in ESRD patients are old age (hazard ratio (HR) 1.17 per 10 years, p
AB - End-stage renal disease (ESRD) patients are vulnerable to Mycobacterium tuberculosis (MTB) infection, but the magnitude of the risk is uncertain. In addition, there is no reliable information on the MTB infection rate of patients undergoing different types of renal replacement therapy (RRT). We used the Taiwan National Health Insurance Research Database to conduct a 9-year nationwide longitudinal study. Among 49983 ESRD patients who received three renal replacement modalities, there were 562 cases of MTB infection, corresponding to an incidence rate of 3.0 per 1000 patient-years. The risk of MTB infection relative to the general population was 4.5. Multivariate Cox regression analysis indicated that the independent risk factors for MTB infection in ESRD patients are old age (hazard ratio (HR) 1.17 per 10 years, p
KW - End-stage renal disease
KW - Mycobacterium tuberculosis
KW - Renal replacement therapy
KW - Taiwan National Health Insurance Research Database
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U2 - 10.1111/j.1469-0691.2011.03473.x
DO - 10.1111/j.1469-0691.2011.03473.x
M3 - Article
C2 - 21375664
AN - SCOPUS:80054083433
SN - 1198-743X
VL - 17
SP - 1646
EP - 1652
JO - Clinical Microbiology and Infection
JF - Clinical Microbiology and Infection
IS - 11
ER -
