TY - JOUR
T1 - Mutagenicity and polycyclic aromatic hydrocarbon content of fumes from heated cooking oils produced in Taiwan
AU - Chiang, Tai An
AU - Wu, Pei Fen
AU - Wang, Li Fang
AU - Lee, Huei
AU - Lee, Chien Hung
AU - Ko, Ying Chin
N1 - Funding Information:
This study was supported by Grants NSC 83-0421-B-037-044Z and 84-2624-B-037-001Z from the National Science Council, Republic of China.
PY - 1997/11/28
Y1 - 1997/11/28
N2 - According to epidemiologic studies, exposure of women to fumes from cooking oils appears to be an important risk factor for lung cancer. Fume samples from three different commercial cooking oils frequently used in Taiwan were collected and analyzed for mutagenicity in the Salmonella/microsome assay. Polycyclic aromatic hydrocarbons were extracted from the samples and identified by HPLC chromatography. Extracts from three cooking oil fumes were found to be mutagenic in the presence of S9 mix. All samples contained dibenz[a,h]anthracene (DB[a,h]A) and benz[a]aothracene (B[a]A). Concentration of DB[a,h]A and B[a]A were 1.9 and 2.2 μg/m3 in fumes from lard oil, 2.1 and 2.3 μg/m3 in soybean oil, 1.8 and 1.3 μg/m3 in peanut oil, respectively. Benzo[a]pyrene (B[a]P) was identified in fume samples of soybean and peanut oil, in concentrations of 19.6 and 18.3 μg/m3, in this order. These results provide experimental evidence and support the findings of epidemiologic observations, in which women exposed to the emitted fumes of cooking oils are at increased risk of contracting lung cancer.
AB - According to epidemiologic studies, exposure of women to fumes from cooking oils appears to be an important risk factor for lung cancer. Fume samples from three different commercial cooking oils frequently used in Taiwan were collected and analyzed for mutagenicity in the Salmonella/microsome assay. Polycyclic aromatic hydrocarbons were extracted from the samples and identified by HPLC chromatography. Extracts from three cooking oil fumes were found to be mutagenic in the presence of S9 mix. All samples contained dibenz[a,h]anthracene (DB[a,h]A) and benz[a]aothracene (B[a]A). Concentration of DB[a,h]A and B[a]A were 1.9 and 2.2 μg/m3 in fumes from lard oil, 2.1 and 2.3 μg/m3 in soybean oil, 1.8 and 1.3 μg/m3 in peanut oil, respectively. Benzo[a]pyrene (B[a]P) was identified in fume samples of soybean and peanut oil, in concentrations of 19.6 and 18.3 μg/m3, in this order. These results provide experimental evidence and support the findings of epidemiologic observations, in which women exposed to the emitted fumes of cooking oils are at increased risk of contracting lung cancer.
KW - Carcinogen
KW - Cooking oil fume
KW - Mutagenicity
KW - Polycyclic aromatic hydrocarbon
UR - https://www.scopus.com/pages/publications/0031589738
UR - https://www.scopus.com/inward/citedby.url?scp=0031589738&partnerID=8YFLogxK
U2 - 10.1016/S0027-5107(97)00163-2
DO - 10.1016/S0027-5107(97)00163-2
M3 - Article
C2 - 9434872
AN - SCOPUS:0031589738
SN - 0027-5107
VL - 381
SP - 157
EP - 161
JO - Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
JF - Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
IS - 2
ER -
