Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation

Wei Chen Huang; Hsin Yi Lai; Li Wei Kuo; Chia Hsin Liao; Po Hsieh Chang; Ta Chung Liu; San Yuan Chen; You Yin Chen

doi:10.1002/adma.201500136

Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation

Wei Chen Huang
, Hsin Yi Lai
, Li Wei Kuo
, Chia Hsin Liao
, Po Hsieh Chang
, Ta Chung Liu
, San Yuan Chen
, You Yin Chen

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.

Original language	English
Pages (from-to)	4186-4193
Number of pages	8
Journal	Advanced Materials
Volume	27
Issue number	28
DOIs	https://doi.org/10.1002/adma.201500136
Publication status	Published - Jul 1 2015
Externally published	Yes

Keywords

drug delivery
hydrogel
nanocarrier(s)
neural implant
neural interface

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

Access to Document

10.1002/adma.201500136

Cite this

@article{afc2f013dbf74fcb993a82e51b1a5f7e,

title = "Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation",

abstract = "To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.",

keywords = "drug delivery, hydrogel, nanocarrier(s), neural implant, neural interface",

author = "Huang, \{Wei Chen\} and Lai, \{Hsin Yi\} and Kuo, \{Li Wei\} and Liao, \{Chia Hsin\} and Chang, \{Po Hsieh\} and Liu, \{Ta Chung\} and Chen, \{San Yuan\} and Chen, \{You Yin\}",

note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim.",

year = "2015",

month = jul,

day = "1",

doi = "10.1002/adma.201500136",

language = "English",

volume = "27",

pages = "4186--4193",

journal = "Advanced Materials",

issn = "0935-9648",

publisher = "Wiley-Blackwell",

number = "28",

}

TY - JOUR

T1 - Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation

AU - Huang, Wei Chen

AU - Lai, Hsin Yi

AU - Kuo, Li Wei

AU - Liao, Chia Hsin

AU - Chang, Po Hsieh

AU - Liu, Ta Chung

AU - Chen, San Yuan

AU - Chen, You Yin

PY - 2015/7/1

Y1 - 2015/7/1

N2 - To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.

AB - To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.

KW - drug delivery

KW - hydrogel

KW - nanocarrier(s)

KW - neural implant

KW - neural interface

UR - https://www.scopus.com/pages/publications/84937142072

UR - https://www.scopus.com/pages/publications/84937142072#tab=citedBy

U2 - 10.1002/adma.201500136

DO - 10.1002/adma.201500136

M3 - Article

C2 - 26074252

AN - SCOPUS:84937142072

SN - 0935-9648

VL - 27

SP - 4186

EP - 4193

JO - Advanced Materials

JF - Advanced Materials

IS - 28

ER -

Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this