Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation

Wei Chen Huang; Hsin Yi Lai; Li Wei Kuo; Chia Hsin Liao; Po Hsieh Chang; Ta Chung Liu; San Yuan Chen; You Yin Chen

doi:10.1002/adma.201500136

Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation

Wei Chen Huang, Hsin Yi Lai, Li Wei Kuo, Chia Hsin Liao, Po Hsieh Chang, Ta Chung Liu, San Yuan Chen, You Yin Chen

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.

Original language	English
Pages (from-to)	4186-4193
Number of pages	8
Journal	Advanced Materials
Volume	27
Issue number	28
DOIs	https://doi.org/10.1002/adma.201500136
Publication status	Published - Jul 1 2015
Externally published	Yes

Keywords

drug delivery
hydrogel
nanocarrier(s)
neural implant
neural interface

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201500136

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title = "Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation",

abstract = "To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.",

keywords = "drug delivery, hydrogel, nanocarrier(s), neural implant, neural interface",

author = "Huang, {Wei Chen} and Lai, {Hsin Yi} and Kuo, {Li Wei} and Liao, {Chia Hsin} and Chang, {Po Hsieh} and Liu, {Ta Chung} and Chen, {San Yuan} and Chen, {You Yin}",

note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",

year = "2015",

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doi = "10.1002/adma.201500136",

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AU - Huang, Wei Chen

AU - Lai, Hsin Yi

AU - Kuo, Li Wei

AU - Liao, Chia Hsin

AU - Chang, Po Hsieh

AU - Liu, Ta Chung

AU - Chen, San Yuan

AU - Chen, You Yin

PY - 2015/7/1

Y1 - 2015/7/1

N2 - To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.

AB - To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.

KW - drug delivery

KW - hydrogel

KW - nanocarrier(s)

KW - neural implant

KW - neural interface

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ER -

Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation

Abstract

Keywords

ASJC Scopus subject areas

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