Multicolor ultra high throughput parallel microfluidic flow cytometer

Y. J. Fan; Yong Chen; Yi Chien Wu; Yu Chun Kung; Tinghsiang Wu; Horn Jiunn Sheen; Pei Yu Chiou

doi:10.1109/Transducers.2013.6627327

Multicolor ultra high throughput parallel microfluidic flow cytometer

Y. J. Fan, Yong Chen, Yi Chien Wu, Yu Chun Kung, Tinghsiang Wu, Horn Jiunn Sheen, Pei Yu Chiou

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

We report an ultrahigh throughput multi-color microfluidic flow cytometer with 32 detection channels and 64 sheath-flow channels. This flow cytometer is realized by integrating a high N.A. microball lens array with a 3D microfluidic device, which allows introducing cell samples into 32 sample channels, and sheath flows into 64 channel for parallel microfluidic focusing using only two inlets. A throughput of 384,000 cell/sec has been accomplished on a single device.

Original language	English
Title of host publication	2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Subtitle of host publication	The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Pages	2556-2559
Number of pages	4
DOIs	https://doi.org/10.1109/Transducers.2013.6627327
Publication status	Published - 2013
Externally published	Yes
Event	2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 - Barcelona, Spain Duration: Jun 16 2013 → Jun 20 2013

Publication series

Name	2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Conference

Conference	2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Country/Territory	Spain
City	Barcelona
Period	6/16/13 → 6/20/13

Keywords

BioMEMS
FACS
flow cytometry
microfluidics

ASJC Scopus subject areas

Hardware and Architecture
Electrical and Electronic Engineering

Access to Document

10.1109/Transducers.2013.6627327

Cite this

Fan, Y. J., Chen, Y., Wu, Y. C., Kung, Y. C., Wu, T., Sheen, H. J., & Chiou, P. Y. (2013). Multicolor ultra high throughput parallel microfluidic flow cytometer. In 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 (pp. 2556-2559). Article 6627327 (2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013). https://doi.org/10.1109/Transducers.2013.6627327

Multicolor ultra high throughput parallel microfluidic flow cytometer. / Fan, Y. J.; Chen, Yong; Wu, Yi Chien et al.
2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013. 2013. p. 2556-2559 6627327 (2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Fan, YJ, Chen, Y, Wu, YC, Kung, YC, Wu, T, Sheen, HJ & Chiou, PY 2013, Multicolor ultra high throughput parallel microfluidic flow cytometer. in 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013., 6627327, 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013, pp. 2556-2559, 2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013, Barcelona, Spain, 6/16/13. https://doi.org/10.1109/Transducers.2013.6627327

Fan YJ, Chen Y, Wu YC, Kung YC, Wu T, Sheen HJ et al. Multicolor ultra high throughput parallel microfluidic flow cytometer. In 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013. 2013. p. 2556-2559. 6627327. (2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013). doi: 10.1109/Transducers.2013.6627327

Fan, Y. J. ; Chen, Yong ; Wu, Yi Chien et al. / Multicolor ultra high throughput parallel microfluidic flow cytometer. 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013. 2013. pp. 2556-2559 (2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013).

@inproceedings{e887c42e9d93441b935b148924293912,

title = "Multicolor ultra high throughput parallel microfluidic flow cytometer",

abstract = "We report an ultrahigh throughput multi-color microfluidic flow cytometer with 32 detection channels and 64 sheath-flow channels. This flow cytometer is realized by integrating a high N.A. microball lens array with a 3D microfluidic device, which allows introducing cell samples into 32 sample channels, and sheath flows into 64 channel for parallel microfluidic focusing using only two inlets. A throughput of 384,000 cell/sec has been accomplished on a single device.",

keywords = "BioMEMS, FACS, flow cytometry, microfluidics",

author = "Fan, {Y. J.} and Yong Chen and Wu, {Yi Chien} and Kung, {Yu Chun} and Tinghsiang Wu and Sheen, {Horn Jiunn} and Chiou, {Pei Yu}",

year = "2013",

doi = "10.1109/Transducers.2013.6627327",

language = "English",

isbn = "9781467359818",

series = "2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013",

pages = "2556--2559",

booktitle = "2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013",

note = "2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 ; Conference date: 16-06-2013 Through 20-06-2013",

}

TY - GEN

T1 - Multicolor ultra high throughput parallel microfluidic flow cytometer

AU - Fan, Y. J.

AU - Chen, Yong

AU - Wu, Yi Chien

AU - Kung, Yu Chun

AU - Wu, Tinghsiang

AU - Sheen, Horn Jiunn

AU - Chiou, Pei Yu

PY - 2013

Y1 - 2013

N2 - We report an ultrahigh throughput multi-color microfluidic flow cytometer with 32 detection channels and 64 sheath-flow channels. This flow cytometer is realized by integrating a high N.A. microball lens array with a 3D microfluidic device, which allows introducing cell samples into 32 sample channels, and sheath flows into 64 channel for parallel microfluidic focusing using only two inlets. A throughput of 384,000 cell/sec has been accomplished on a single device.

AB - We report an ultrahigh throughput multi-color microfluidic flow cytometer with 32 detection channels and 64 sheath-flow channels. This flow cytometer is realized by integrating a high N.A. microball lens array with a 3D microfluidic device, which allows introducing cell samples into 32 sample channels, and sheath flows into 64 channel for parallel microfluidic focusing using only two inlets. A throughput of 384,000 cell/sec has been accomplished on a single device.

KW - BioMEMS

KW - FACS

KW - flow cytometry

KW - microfluidics

UR - http://www.scopus.com/inward/record.url?scp=84891704660&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84891704660&partnerID=8YFLogxK

U2 - 10.1109/Transducers.2013.6627327

DO - 10.1109/Transducers.2013.6627327

M3 - Conference contribution

AN - SCOPUS:84891704660

SN - 9781467359818

T3 - 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

SP - 2556

EP - 2559

BT - 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

T2 - 2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Y2 - 16 June 2013 through 20 June 2013

ER -

Multicolor ultra high throughput parallel microfluidic flow cytometer

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this