Multicentric reticulohistiocytosis in a Taiwanese woman with Sjögren syndrome

Lan hsin Cheng, Ying Yi Chiang

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Multicentric reticulohistiocytosis is a rare, non-Langerhans cell histiocytosis characterized by specific skin lesions and destructive arthritis. Clinically, it generally presents with multiple reddish-brown papulonodules over the hands, face, and trunk. The associated destructive arthropathy tends to be severe, with 50% of patients developing arthritis mutilans. Approximately 25-30% of patients present with neoplasia. Coexisting autoimmune diseases are also commonly reported. Here we report the case of a 59-year-old Taiwanese woman with underlying Sjögren syndrome who presented with the typical skin manifestations of multicentric reticulohistiocytosis and early interphalangeal joint involvement. The patient later showed partial response to methotrexate treatment.

Original languageEnglish
Pages (from-to)42-45
JournalDermatologica Sinica
Issue number1
Publication statusPublished - Mar 1 2016


  • Dermatomyositis
  • Erosive polyarthropathy
  • Multicentric reticulohistiocytosis
  • Non-langerhans cell histiocytosis
  • Sjögren syndrome

ASJC Scopus subject areas

  • Dermatology


Dive into the research topics of 'Multicentric reticulohistiocytosis in a Taiwanese woman with Sjögren syndrome'. Together they form a unique fingerprint.

Cite this