Monostotic vertebral Paget's disease of the lumbar spine

Lien Chen Wu, Chun Hsiung Tseng, Yueh Feng Chiang, Yang Hwei Tsuang

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Paget's disease in the Far East is quite rare. Age at diagnosis is usually greater than 50 years, and the disease typically affects the spine. Most patients are usually diagnosed with Paget's disease following radiographic examination for other purposes. It usually occurs at multiple vertebral levels, with only 10-25% of vertebral Paget's disease being monostotic. The disease rarely causes neurologic complications resulting from compression of intraspinal nerve tissue. Here, we present 2 cases of monostotic vertebral Paget's disease of the third lumbar vertebra. The first patient, who may be the first documented case of Paget's disease in the lumbar spine with progressive neurologic deficiency in an Asian population, received decompressive laminectomy due to marked spinal stenosis with neurologic deficits. The symptoms were greatly relieved following surgery, and ambulatory ability was restored. The second patient was diagnosed with Paget's disease following surgical biopsy. He remained asymptomatic at the most recent follow-up.

Original languageEnglish
Pages (from-to)52-55
Number of pages4
JournalJournal of the Chinese Medical Association
Issue number1
Publication statusPublished - Jan 2009
Externally publishedYes


  • Lumbar vertebra
  • Paget's disease
  • Spinal stenosis

ASJC Scopus subject areas

  • Medicine(all)


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