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Minor groove-directed and intercalative ligand-DNA interactions in the poisoning of human DNA topoisomerase I by protoberberine analogs

  • Daniel S. Pilch
  • , Chiang Yu
  • , Darshan Makhey
  • , Edmond J. LaVoie
  • , A. R. Srinivasan
  • , Wilma K. Olson
  • , Ronald R. Sauers
  • , Kenneth J. Breslauer
  • , Nicholas E. Geacintov
  • , Leroy F. Liu

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