MicroRNA in lung cancer

P. Y. Lin; S. L. Yu; P. C. Yang

doi:10.1038/sj.bjc.6605901

MicroRNA in lung cancer

P. Y. Lin, S. L. Yu, P. C. Yang

Research output: Contribution to journal › Short survey › peer-review

202 Citations (Scopus)

Abstract

MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction.

Original language	English
Pages (from-to)	1144-1148
Number of pages	5
Journal	British Journal of Cancer
Volume	103
Issue number	8
DOIs	https://doi.org/10.1038/sj.bjc.6605901
Publication status	Published - Oct 12 2010

Keywords

lung cancer
microRNA
oncogene
personalised medicine
risk stratification
tumour suppressor

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/sj.bjc.6605901

Cite this

@article{b8b51f793c6d443296aabd3f7d541ba0,

title = "MicroRNA in lung cancer",

abstract = "MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction.",

keywords = "lung cancer, microRNA, oncogene, personalised medicine, risk stratification, tumour suppressor",

author = "Lin, {P. Y.} and Yu, {S. L.} and Yang, {P. C.}",

year = "2010",

month = oct,

day = "12",

doi = "10.1038/sj.bjc.6605901",

language = "English",

volume = "103",

pages = "1144--1148",

journal = "British Journal of Cancer",

issn = "0007-0920",

publisher = "Nature Publishing Group",

number = "8",

}

TY - JOUR

T1 - MicroRNA in lung cancer

AU - Lin, P. Y.

AU - Yu, S. L.

AU - Yang, P. C.

PY - 2010/10/12

Y1 - 2010/10/12

N2 - MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction.

AB - MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction.

KW - lung cancer

KW - microRNA

KW - oncogene

KW - personalised medicine

KW - risk stratification

KW - tumour suppressor

UR - http://www.scopus.com/inward/record.url?scp=77957982985&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77957982985&partnerID=8YFLogxK

U2 - 10.1038/sj.bjc.6605901

DO - 10.1038/sj.bjc.6605901

M3 - Short survey

C2 - 20859290

AN - SCOPUS:77957982985

SN - 0007-0920

VL - 103

SP - 1144

EP - 1148

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 8

ER -

MicroRNA in lung cancer

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this