Microfluidic devices for aiding in-vitro fertilization technique

Yung Chin Tzeng; Yueh Jen Chen; Chang Chuan; Li Chen Pan; Fan Gang Tseng

doi:10.1109/NEMS.2017.8016993

Microfluidic devices for aiding in-vitro fertilization technique

Yung Chin Tzeng, Yueh Jen Chen, Chang Chuan, Li Chen Pan, Fan Gang Tseng

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In this study, we propose two devices that provide an easier and faster method to execute in-vitro fertilization (IVF) technique. The devices consist of a high quality sperm sorter and an oocytes zona-removal and incubation device to aid promoting the success rate and the efficiency of IVF technique. Comparing with the traditional IVF process, the high quality sperm sorter can gently sort out large number of sperms in few minutes and keep high survival rate for oligospermia patients. At the same time, the oocytes zona-removal and incubation device also gently decreases the enzyme contraction with removing oocytes shell rapidly. Experiment results showed that sorted sperms could easily attach on dezona oocytes surface, and the oocytes are still in complete shape. These two devices not only provide an easier and faster method to sort out motile sperms and dezona oocytes, but also increase the attachment rate of sperms on oocytes.

Original language	English
Title of host publication	2017 IEEE 12th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	147-150
Number of pages	4
ISBN (Electronic)	9781509030590
DOIs	https://doi.org/10.1109/NEMS.2017.8016993
Publication status	Published - Aug 25 2017
Event	12th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017 - Los Angeles, United States Duration: Apr 9 2017 → Apr 12 2017

Other

Other	12th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017
Country/Territory	United States
City	Los Angeles
Period	4/9/17 → 4/12/17

ASJC Scopus subject areas

Electrical and Electronic Engineering
Mechanical Engineering
Electronic, Optical and Magnetic Materials
Instrumentation

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10.1109/NEMS.2017.8016993

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Microfluidic devices for aiding in-vitro fertilization technique. / Tzeng, Yung Chin; Chen, Yueh Jen; Chuan, Chang et al.
2017 IEEE 12th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017. Institute of Electrical and Electronics Engineers Inc., 2017. p. 147-150 8016993.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Tzeng, YC, Chen, YJ, Chuan, C, Pan, LC & Tseng, FG 2017, Microfluidic devices for aiding in-vitro fertilization technique. in 2017 IEEE 12th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017., 8016993, Institute of Electrical and Electronics Engineers Inc., pp. 147-150, 12th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017, Los Angeles, United States, 4/9/17. https://doi.org/10.1109/NEMS.2017.8016993

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title = "Microfluidic devices for aiding in-vitro fertilization technique",

abstract = "In this study, we propose two devices that provide an easier and faster method to execute in-vitro fertilization (IVF) technique. The devices consist of a high quality sperm sorter and an oocytes zona-removal and incubation device to aid promoting the success rate and the efficiency of IVF technique. Comparing with the traditional IVF process, the high quality sperm sorter can gently sort out large number of sperms in few minutes and keep high survival rate for oligospermia patients. At the same time, the oocytes zona-removal and incubation device also gently decreases the enzyme contraction with removing oocytes shell rapidly. Experiment results showed that sorted sperms could easily attach on dezona oocytes surface, and the oocytes are still in complete shape. These two devices not only provide an easier and faster method to sort out motile sperms and dezona oocytes, but also increase the attachment rate of sperms on oocytes.",

author = "Tzeng, {Yung Chin} and Chen, {Yueh Jen} and Chang Chuan and Pan, {Li Chen} and Tseng, {Fan Gang}",

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PY - 2017/8/25

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AB - In this study, we propose two devices that provide an easier and faster method to execute in-vitro fertilization (IVF) technique. The devices consist of a high quality sperm sorter and an oocytes zona-removal and incubation device to aid promoting the success rate and the efficiency of IVF technique. Comparing with the traditional IVF process, the high quality sperm sorter can gently sort out large number of sperms in few minutes and keep high survival rate for oligospermia patients. At the same time, the oocytes zona-removal and incubation device also gently decreases the enzyme contraction with removing oocytes shell rapidly. Experiment results showed that sorted sperms could easily attach on dezona oocytes surface, and the oocytes are still in complete shape. These two devices not only provide an easier and faster method to sort out motile sperms and dezona oocytes, but also increase the attachment rate of sperms on oocytes.

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Microfluidic devices for aiding in-vitro fertilization technique

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