Microbiologic and histologic diagnosis of histoplasmosis in Taiwan

Tze Wah Kao, Chien Ching Hung, Po Ren Hsueh, Tzou Yien Lin, Mao Yuan Chen, Kwen Tay Luh, Chi Yen Chuang

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Histoplasmosis is one of the most common opportunistic fungal infections in immunocompromoised patients in endemic areas. We report the first two microbiologically documented cases of histoplasmosis in Taiwan. The first patient, with acquired immunodeficiency syndrome and a depleted CD4+ lymphocyte count, presented with a history of prolonged fever, papular skin rashes, pancytopenia and elevation of liver enzymes. He was diagnosed and treated initially for systematic toxoplasmosis, but the microbiologic and pathologic findings of the autopsied specimens disclosed disseminated infection caused by Histoplasma capsulatum. The second patient, an elderly man receiving corticosteroids for adrenal insufficiency, manifested with laryngeal histoplasmosis and was successfully treated with ketoconazole.

Original languageEnglish
Pages (from-to)374-378
Number of pages5
JournalJournal of the Formosan Medical Association
Issue number5
Publication statusPublished - May 1997
Externally publishedYes


  • AIDS
  • Disseminated histoplasmosis
  • Histoplasma capsulatum
  • Laryngeal histoplasmosis

ASJC Scopus subject areas

  • General Medicine


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