TY - JOUR
T1 - Metastatic choroidal tumors in Taiwan
T2 - An 11-year experience
AU - Wang, Tsung Jen
AU - Yang, Chung May
AU - Ho, Tzyy Chang
AU - Huang, Jen Shang
AU - Lin, Chang Pin
AU - Yang, Chang Hao
AU - Chen, Muh Shy
AU - Lin, Luke Long Kuang
PY - 2005/10
Y1 - 2005/10
N2 - PURPOSE: To report the clinical features, the primary sites, and overall prognosis of choroidal metastasis. DESIGN: Observational case series. METHODS: Included were all cases of choroidal metastases evaluated at National Taiwan University Hospital over an 11-year period. Patients with blood or lymphoproliferative diseases were excluded. Clinical features were correlated with disease entity and prognosis. RESULTS: A total of 36 patients with choroidal metastases were identified. The mean age was 53.9 ± 12.8 years. The mean follow-up period was 5.1 ± 4.2 months. The primary sites of tumors were lung in 18 (50%), breast in eight (22.2%), gastrointestinal tract in three (8.3%), pancreas in two (5.6%), ovary in two (5.6%), kidney in one (2.8%), liver in one (2.8%), and unknown in one (2.8%). Twenty-two patients (61%) died during follow-up. Mean life span after diagnosis was 4.3 months in these 22 patients. CONCLUSIONS: Lung and breast cancers represent more than two thirds of primary tumor sites. Choroidal metastases may indicate terminal status of the underlying malignancy and short survival time.
AB - PURPOSE: To report the clinical features, the primary sites, and overall prognosis of choroidal metastasis. DESIGN: Observational case series. METHODS: Included were all cases of choroidal metastases evaluated at National Taiwan University Hospital over an 11-year period. Patients with blood or lymphoproliferative diseases were excluded. Clinical features were correlated with disease entity and prognosis. RESULTS: A total of 36 patients with choroidal metastases were identified. The mean age was 53.9 ± 12.8 years. The mean follow-up period was 5.1 ± 4.2 months. The primary sites of tumors were lung in 18 (50%), breast in eight (22.2%), gastrointestinal tract in three (8.3%), pancreas in two (5.6%), ovary in two (5.6%), kidney in one (2.8%), liver in one (2.8%), and unknown in one (2.8%). Twenty-two patients (61%) died during follow-up. Mean life span after diagnosis was 4.3 months in these 22 patients. CONCLUSIONS: Lung and breast cancers represent more than two thirds of primary tumor sites. Choroidal metastases may indicate terminal status of the underlying malignancy and short survival time.
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U2 - 10.1016/j.ajo.2005.03.068
DO - 10.1016/j.ajo.2005.03.068
M3 - Article
C2 - 16226531
AN - SCOPUS:26844435799
SN - 0002-9394
VL - 140
SP - 735
EP - 737
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 4
ER -