Abstract
Purpose: The aim of this study was to identify an anatomical relationship between deep medullary vein and these three
common brain tumors, which may improve preoperative diagnostic accuracy.
Materials and Methods: Patients with SWI studies of the brain and pathology-confirmed PCNSL, high-grade glioma,
or intraaxial metastatic lesions between 2009 and 2015 were reviewed. On SWI, those whose deep medullary veins
could be visualized within 5-mm range of the enhancing tumor were enrolled into the study. A total of 27 patients were
recruited and images were reviewed for signs of medullary vein blockage (MVB). MVB was defined as a deep
medullary vein terminating at the margin of the tumor. The sensitivity, specificity, and diagnostic accuracy of MVB in
differentiating PCNSL, high-grade glioma, and metastasis were analyzed.
Results: A total of 11 PCNSL, 5 high-grade gliomas, and 11 metastatic cases were reviewed. MVB was not identified
in any of imaging studies for PCNSL or high-grade glioma patients. However, MVB was noted in 9 of 11 metastatic
tumors (81.8%). The MVB sign showed a diagnostic specificity and accuracy of 100% and 92.6%, respectively, for
intraaxial metastatic tumors.
Conclusion: The MVB sign on SWI images has a high accuracy and specificity for differentiating metastatic brain
tumors from PCNSL, high-grade gliomas and thus may aid physicians in treatment planning.
common brain tumors, which may improve preoperative diagnostic accuracy.
Materials and Methods: Patients with SWI studies of the brain and pathology-confirmed PCNSL, high-grade glioma,
or intraaxial metastatic lesions between 2009 and 2015 were reviewed. On SWI, those whose deep medullary veins
could be visualized within 5-mm range of the enhancing tumor were enrolled into the study. A total of 27 patients were
recruited and images were reviewed for signs of medullary vein blockage (MVB). MVB was defined as a deep
medullary vein terminating at the margin of the tumor. The sensitivity, specificity, and diagnostic accuracy of MVB in
differentiating PCNSL, high-grade glioma, and metastasis were analyzed.
Results: A total of 11 PCNSL, 5 high-grade gliomas, and 11 metastatic cases were reviewed. MVB was not identified
in any of imaging studies for PCNSL or high-grade glioma patients. However, MVB was noted in 9 of 11 metastatic
tumors (81.8%). The MVB sign showed a diagnostic specificity and accuracy of 100% and 92.6%, respectively, for
intraaxial metastatic tumors.
Conclusion: The MVB sign on SWI images has a high accuracy and specificity for differentiating metastatic brain
tumors from PCNSL, high-grade gliomas and thus may aid physicians in treatment planning.
| Translated title of the contribution | 磁敏感加權造影偵測之腦髓質靜脈阻斷徵象診斷腦部轉移腫瘤 |
|---|---|
| Original language | English |
| Publication status | Published - Mar 2017 |
| Event | The 66th Annual Meeting of RSROC - NTUH International Convention Center, Taipei, Taiwan Duration: Mar 18 2017 → Mar 19 2017 https://www.rsroc.org.tw/annual/annualnews_detail.asp?id=93 |
Conference
| Conference | The 66th Annual Meeting of RSROC |
|---|---|
| Country/Territory | Taiwan |
| City | Taipei |
| Period | 3/18/17 → 3/19/17 |
| Internet address |