TY - JOUR
T1 - Medical costs and vasculometabolic comorbidities among patients with bipolar disorder in Taiwan - A population-based and matched-control study
AU - Hsieh, Ming Hong
AU - Tang, Chao Hsiun
AU - Hsieh, Ming H.
AU - Lee, I. Hui
AU - Lai, Te Jen
AU - Lin, Yung Jung
AU - Yang, Yen Kuang
N1 - Funding Information:
The authors extend their sincere appreciation to Janssen-Cilag (Taiwan) for funding this research.
Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012/12/10
Y1 - 2012/12/10
N2 - Background: Bipolar disorder (BD) is a costly disease with a high rate of vasculometabolic comorbidities. The aims of this study were to explore the 1-year treatment cost, including total medical and non-psychiatric services, and the prevalence of vasculometabolic comorbidities in individuals with BD. Methods: A nationwide population-based dataset, covering the years 2006 and 2007, was obtained from the Taiwan National Health Insurance claims database. The study sample comprised patients discharged from hospitals between 1 January 2006 and 31 December 2007. Annual non-psychiatric and total medical costs and vasculometabolic comorbidities were examined. Generalized linear models were used to examine the medical costs, and conditional logistic regression analyses were carried out to test the prevalence of vasculometabolic comorbidities in people with BD and to compare this with that found in matched controls. Results: The total medical cost was 11-fold higher (New Taiwan [NT] $227,040 vs. NT$20,461), and the non-psychiatric medical cost was 1.7-fold higher (NT$33,173 vs. NT$19,406) with regard to the individuals with BD vs. the matched controls. The prevalence of vasculometabolic comorbidities was significantly higher in the individuals with BD than in the controls (ratio ranging from 1.86 to 4.06). Conclusions: Both the non-psychiatric healthcare utilization and the prevalence of vasculometabolic comorbidities are higher with regard to individuals with BD vs. their matched controls. Therefore, treatment of BD should integrate medical and psychiatric care to decrease the impact of medical comorbidities, which may also decrease the overall medical cost.
AB - Background: Bipolar disorder (BD) is a costly disease with a high rate of vasculometabolic comorbidities. The aims of this study were to explore the 1-year treatment cost, including total medical and non-psychiatric services, and the prevalence of vasculometabolic comorbidities in individuals with BD. Methods: A nationwide population-based dataset, covering the years 2006 and 2007, was obtained from the Taiwan National Health Insurance claims database. The study sample comprised patients discharged from hospitals between 1 January 2006 and 31 December 2007. Annual non-psychiatric and total medical costs and vasculometabolic comorbidities were examined. Generalized linear models were used to examine the medical costs, and conditional logistic regression analyses were carried out to test the prevalence of vasculometabolic comorbidities in people with BD and to compare this with that found in matched controls. Results: The total medical cost was 11-fold higher (New Taiwan [NT] $227,040 vs. NT$20,461), and the non-psychiatric medical cost was 1.7-fold higher (NT$33,173 vs. NT$19,406) with regard to the individuals with BD vs. the matched controls. The prevalence of vasculometabolic comorbidities was significantly higher in the individuals with BD than in the controls (ratio ranging from 1.86 to 4.06). Conclusions: Both the non-psychiatric healthcare utilization and the prevalence of vasculometabolic comorbidities are higher with regard to individuals with BD vs. their matched controls. Therefore, treatment of BD should integrate medical and psychiatric care to decrease the impact of medical comorbidities, which may also decrease the overall medical cost.
KW - Bipolar disorder
KW - Non-psychiatric medical cost
KW - Total medical cost
KW - Vasculometabolic comorbidity
UR - http://www.scopus.com/inward/record.url?scp=84867583156&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84867583156&partnerID=8YFLogxK
U2 - 10.1016/j.jad.2012.02.038
DO - 10.1016/j.jad.2012.02.038
M3 - Article
C2 - 22460055
AN - SCOPUS:84867583156
SN - 0165-0327
VL - 141
SP - 449
EP - 456
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
IS - 2-3
ER -