Mechanical unfolding and refolding of proteins: An off-lattice model study

Feng Yin Li, Jian Min Yuan, Cluing Yuan Mou

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Using an off-lattice model, we investigate the response of a protein molecule to external stretching and release. In particular we study the passive force in a protein as a function of the extension of the protein. These force-extension curves exhibit hysteresis loops, whose areas increase with the pulling rate and decrease with thermal noise. Most of these results seem to be appropriately described by a cusp catastrophe.

Original languageEnglish
Article number021905
Pages (from-to)219051-2190510
Number of pages1971460
JournalPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
Volume63
Issue number2 I
DOIs
Publication statusPublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • General Physics and Astronomy
  • Condensed Matter Physics
  • Statistical and Nonlinear Physics
  • Mathematical Physics
  • General Medicine

Fingerprint

Dive into the research topics of 'Mechanical unfolding and refolding of proteins: An off-lattice model study'. Together they form a unique fingerprint.

Cite this