Mast cell leukemia: An extremely rare disease

Dai Yin Lu; Jyh Pyng Gau; Ying Chung Hong; Chun Yu Liu; Yuan Bin Yu; Liang Tsai Hsiao; Jin Hwang Liu; Po Min Chen; Tzeon Jye Chiou; Cheng Hwai Tzeng

doi:10.1016/j.jcma.2014.05.004

Mast cell leukemia: An extremely rare disease

Dai Yin Lu, Jyh Pyng Gau, Ying Chung Hong, Chun Yu Liu, Yuan Bin Yu, Liang Tsai Hsiao, Jin Hwang Liu, Po Min Chen, Tzeon Jye Chiou, Cheng Hwai Tzeng

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Systemic mastocytosis is characterized by pathologic proliferation and accumulation of mast cells in at least one extracutaneous organ such as liver, spleen, bone marrow, or lymph nodes. The clinical features are highly variable depending on impairment of the involved organ systems. It often raises diagnostic challenges. Here we report a case of a 78-year-old patient with mast cell leukemia. The literature is reviewed regarding the diagnosis and updated management of this rare disease.

Original language	English
Pages (from-to)	446-449
Number of pages	4
Journal	Journal of the Chinese Medical Association
Volume	77
Issue number	8
DOIs	https://doi.org/10.1016/j.jcma.2014.05.004
Publication status	Published - Aug 2014
Externally published	Yes

Keywords

Interferon
KITD816V
Systemic mastocytosis
Tyrosine kinase inhibitor

ASJC Scopus subject areas

Medicine(all)

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10.1016/j.jcma.2014.05.004

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title = "Mast cell leukemia: An extremely rare disease",

abstract = "Systemic mastocytosis is characterized by pathologic proliferation and accumulation of mast cells in at least one extracutaneous organ such as liver, spleen, bone marrow, or lymph nodes. The clinical features are highly variable depending on impairment of the involved organ systems. It often raises diagnostic challenges. Here we report a case of a 78-year-old patient with mast cell leukemia. The literature is reviewed regarding the diagnosis and updated management of this rare disease.",

keywords = "Interferon, KITD816V, Systemic mastocytosis, Tyrosine kinase inhibitor",

author = "Lu, {Dai Yin} and Gau, {Jyh Pyng} and Hong, {Ying Chung} and Liu, {Chun Yu} and Yu, {Yuan Bin} and Hsiao, {Liang Tsai} and Liu, {Jin Hwang} and Chen, {Po Min} and Chiou, {Tzeon Jye} and Tzeng, {Cheng Hwai}",

year = "2014",

month = aug,

doi = "10.1016/j.jcma.2014.05.004",

language = "English",

volume = "77",

pages = "446--449",

journal = "Journal of the Chinese Medical Association",

issn = "1726-4901",

publisher = "Elsevier Taiwan LLC",

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TY - JOUR

T1 - Mast cell leukemia

T2 - An extremely rare disease

AU - Lu, Dai Yin

AU - Gau, Jyh Pyng

AU - Hong, Ying Chung

AU - Liu, Chun Yu

AU - Yu, Yuan Bin

AU - Hsiao, Liang Tsai

AU - Liu, Jin Hwang

AU - Chen, Po Min

AU - Chiou, Tzeon Jye

AU - Tzeng, Cheng Hwai

PY - 2014/8

Y1 - 2014/8

N2 - Systemic mastocytosis is characterized by pathologic proliferation and accumulation of mast cells in at least one extracutaneous organ such as liver, spleen, bone marrow, or lymph nodes. The clinical features are highly variable depending on impairment of the involved organ systems. It often raises diagnostic challenges. Here we report a case of a 78-year-old patient with mast cell leukemia. The literature is reviewed regarding the diagnosis and updated management of this rare disease.

AB - Systemic mastocytosis is characterized by pathologic proliferation and accumulation of mast cells in at least one extracutaneous organ such as liver, spleen, bone marrow, or lymph nodes. The clinical features are highly variable depending on impairment of the involved organ systems. It often raises diagnostic challenges. Here we report a case of a 78-year-old patient with mast cell leukemia. The literature is reviewed regarding the diagnosis and updated management of this rare disease.

KW - Interferon

KW - KITD816V

KW - Systemic mastocytosis

KW - Tyrosine kinase inhibitor

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DO - 10.1016/j.jcma.2014.05.004

M3 - Article

C2 - 25028296

AN - SCOPUS:84906279354

SN - 1726-4901

VL - 77

SP - 446

EP - 449

JO - Journal of the Chinese Medical Association

JF - Journal of the Chinese Medical Association

IS - 8

ER -

Mast cell leukemia: An extremely rare disease

Abstract

Keywords

ASJC Scopus subject areas

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