Management of oligohydramnios with antepartum amnioinfusion, amniopatch and cerclage

Ming Chen, Chang Yao Hsieh, Alan D. Cameron, Jin Chung Shih, Chien Nan Lee, Hong Nerng Ho, Tze Ho Chen, Chih Ping Chen

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Objective: To evaluate the efficacy and safety of aggressive management of oligohydramnios. Methods: Forty women with oligohydramnios (< 30 complete weeks), either because of preterm premature rupture of membranes or with intact membranes, were prospectively enrolled in this study. Eleven women were assigned to the treatment group and 29 to the control group. Transabdominal amnioinfusion was performed with warm Ringer's lactate or normal saline in all 11 patients in the treatment group. In addition, cerclage was performed in patients with ruptured amniotic membranes. Amniopatch was used to salvage a patient with immediate amniorrhea (< 6 hours) after the above procedures. Results: Nine of the 11 patients prolonged their pregnancy for at least 3 weeks (81.8%), while all 29 patients in the control group delivered their babies within 3 weeks of diagnosis of oligohydramnios (p < 0.05). Signs of maternal infection were noted in two patients in the treatment group (18.2%). The newborns of eight patients in the treatment group survived beyond 1 month (72.7%), whereas this occurred in only six control patients (20.7%; p < 0.05). Conclusion: Aggressive management seemed to provide prolongation of pregnancy compared with no treatment. Amniopatch salvaged the immediate amniorrhea in our patient.

Original languageEnglish
Pages (from-to)347-352
Number of pages6
JournalTaiwanese Journal of Obstetrics and Gynecology
Issue number4
Publication statusPublished - Jan 1 2005
Externally publishedYes


  • Amnioinfusion
  • Amniopatch
  • Cerclage
  • Oligohydramnios
  • Preterm premature rupture of membranes

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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