Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-κB signaling pathways

Medicine & Life Sciences

• magnolol 95%
• Proto-Oncogene Proteins c-akt 68%
• Mitogen-Activated Protein Kinases 57%
• Lipopolysaccharides 49%
• Down-Regulation 40%
• Biphenyl Compounds 13%
• Magnolia 11%
• 1-Phosphatidylinositol 4-Kinase 10%
• Phosphorylation 10%
• RAW 264.7 Cells 9%
• Gene Expression 8%
• Inflammation 8%
• Mitogen-Activated Protein Kinase 3 8%
• Mitogen-Activated Protein Kinase 1 8%
• p38 Mitogen-Activated Protein Kinases 7%
• Phosphatidylinositol 3-Kinases 7%
• Nitric Oxide Synthase 7%
• Phosphotransferases 5%
• Anti-Inflammatory Agents 5%
• Proteins 5%
• Macrophages 5%
• Western Blotting 4%

Agriculture & Biology

• magnolol 100%
• prostaglandin synthase 64%
• mitogen-activated protein kinase 62%
• lipopolysaccharides 55%
• inflammation 13%
• phosphorylation 12%
• phosphotransferases (kinases) 12%
• Magnolia officinalis 12%
• protein synthesis 10%
• anti-inflammatory agents 9%
• phosphatidylinositol 3-kinase 9%
• gene expression 8%
• biphenyl 7%
• crossover interference 7%
• macrophages 6%
• bark 6%
• Western blotting 6%
• degradation 4%
• mice 4%
• assays 3%
• cells 2%