LUTEOLIN AFFECTS CELL PROLIFERTATION, CELL INVASION AND PROSTATE-SPECIFIC ANTIGEN EXPRESSION BY DYREGULATION OF PROSTATE-DERIVED ETS FACTOR AND ANDROGEN RECEPTOR EXPRESSION IN PROSTATE CARCINOMA LNCAP CELLS

Tsui Ke-Hung; Juang Horng-Heng

doi:10.1016/S0022-5347(09)61124-1

LUTEOLIN AFFECTS CELL PROLIFERTATION, CELL INVASION AND PROSTATE-SPECIFIC ANTIGEN EXPRESSION BY DYREGULATION OF PROSTATE-DERIVED ETS FACTOR AND ANDROGEN RECEPTOR EXPRESSION IN PROSTATE CARCINOMA LNCAP CELLS

Tsui Ke-Hung
, Juang Horng-Heng

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose:
We searched for bladder tumor markers by analyzing urine samples from patients with bladder cancer and normal individuals.

Materials and Methods:
Proteins in urine samples of patients with cancer and normal subjects were systematically examined by 2-dimensional electrophoresis combined with matrix assisted laser desorption ionization time-of-flight mass spectrometry. Of the proteins bikunin expression was confirmed by Western blot analysis and further evaluated. To correlate urinary bikunin levels with clinical significance we examined urine samples from patients with bladder cancer and normal controls for bikunin expression in parallel with pro-urolinase-plasminogen activator, which was previously shown to be associated with advanced bladder carcinoma.

Results:
A significant relationship was established between the low level and absence of bikunin, and pro-urolinase-plasminogen activator in urine samples from patients with bladder tumors.

Original language	Chinese (Traditional)
Pages (from-to)	396
Number of pages	1
Journal	Journal of Urology
Volume	181
Issue number	4S
DOIs	https://doi.org/10.1016/S0022-5347(09)61124-1
Publication status	Published - 2009

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/S0022-5347(09)61124-1

https://doi.org/10.1016/S0022-5347(09)61124-1

Cite this

@article{f1edd7f24b224969bc755326ea524918,

title = "LUTEOLIN AFFECTS CELL PROLIFERTATION, CELL INVASION AND PROSTATE-SPECIFIC ANTIGEN EXPRESSION BY DYREGULATION OF PROSTATE-DERIVED ETS FACTOR AND ANDROGEN RECEPTOR EXPRESSION IN PROSTATE CARCINOMA LNCAP CELLS",

abstract = "Purpose: We searched for bladder tumor markers by analyzing urine samples from patients with bladder cancer and normal individuals. Materials and Methods: Proteins in urine samples of patients with cancer and normal subjects were systematically examined by 2-dimensional electrophoresis combined with matrix assisted laser desorption ionization time-of-flight mass spectrometry. Of the proteins bikunin expression was confirmed by Western blot analysis and further evaluated. To correlate urinary bikunin levels with clinical significance we examined urine samples from patients with bladder cancer and normal controls for bikunin expression in parallel with pro-urolinase-plasminogen activator, which was previously shown to be associated with advanced bladder carcinoma. Results: A significant relationship was established between the low level and absence of bikunin, and pro-urolinase-plasminogen activator in urine samples from patients with bladder tumors.",

author = "Tsui Ke-Hung and Juang Horng-Heng",

note = "doi: 10.1016/S0022-5347(09)61124-1",

year = "2009",

doi = "10.1016/S0022-5347(09)61124-1",

language = "中文",

volume = "181",

pages = "396",

journal = "Journal of Urology",

issn = "0022-5347",

publisher = "Wolters Kluwer Health",

number = "4S",

}

TY - JOUR

T1 - LUTEOLIN AFFECTS CELL PROLIFERTATION, CELL INVASION AND PROSTATE-SPECIFIC ANTIGEN EXPRESSION BY DYREGULATION OF PROSTATE-DERIVED ETS FACTOR AND ANDROGEN RECEPTOR EXPRESSION IN PROSTATE CARCINOMA LNCAP CELLS

AU - Ke-Hung, Tsui

AU - Horng-Heng, Juang

N1 - doi: 10.1016/S0022-5347(09)61124-1

PY - 2009

Y1 - 2009

N2 - Purpose: We searched for bladder tumor markers by analyzing urine samples from patients with bladder cancer and normal individuals. Materials and Methods: Proteins in urine samples of patients with cancer and normal subjects were systematically examined by 2-dimensional electrophoresis combined with matrix assisted laser desorption ionization time-of-flight mass spectrometry. Of the proteins bikunin expression was confirmed by Western blot analysis and further evaluated. To correlate urinary bikunin levels with clinical significance we examined urine samples from patients with bladder cancer and normal controls for bikunin expression in parallel with pro-urolinase-plasminogen activator, which was previously shown to be associated with advanced bladder carcinoma. Results: A significant relationship was established between the low level and absence of bikunin, and pro-urolinase-plasminogen activator in urine samples from patients with bladder tumors.

AB - Purpose: We searched for bladder tumor markers by analyzing urine samples from patients with bladder cancer and normal individuals. Materials and Methods: Proteins in urine samples of patients with cancer and normal subjects were systematically examined by 2-dimensional electrophoresis combined with matrix assisted laser desorption ionization time-of-flight mass spectrometry. Of the proteins bikunin expression was confirmed by Western blot analysis and further evaluated. To correlate urinary bikunin levels with clinical significance we examined urine samples from patients with bladder cancer and normal controls for bikunin expression in parallel with pro-urolinase-plasminogen activator, which was previously shown to be associated with advanced bladder carcinoma. Results: A significant relationship was established between the low level and absence of bikunin, and pro-urolinase-plasminogen activator in urine samples from patients with bladder tumors.

U2 - 10.1016/S0022-5347(09)61124-1

DO - 10.1016/S0022-5347(09)61124-1

M3 - 文章

SN - 0022-5347

VL - 181

SP - 396

JO - Journal of Urology

JF - Journal of Urology

IS - 4S

ER -