Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells

Yuh Ming Hwu; Sheng Hsiang Li; Robert Kuo kuang Lee; Ming Huei Lin; Yu Hui Tsai; Tian-Shun Tsai

doi:10.1016/j.fertnstert.2009.05.064

Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells

Yuh Ming Hwu
, Sheng Hsiang Li
, Robert Kuo kuang Lee
, Ming Huei Lin
, Yu Hui Tsai
, Tian-Shun Tsai

Graduate Institute of Medical Sciences

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

We aimed to investigate the effects of LH and FSH on the gene expression of the platelet-derived growth factor (PDGF) gene family in human granulosa-luteal cells. We found that LH significantly increased PDGF-D messenger RNA (mRNA) expression but suppressed PDGF-B and PDGF-C mRNA in human granulosa-luteal cells, and FSH also increases PDGF-D gene expression, but to a lesser extent.

Original language	English
Pages (from-to)	2065-2068
Number of pages	4
Journal	Fertility and Sterility
Volume	92
Issue number	6
DOIs	https://doi.org/10.1016/j.fertnstert.2009.05.064
Publication status	Published - Dec 2009

ASJC Scopus subject areas

Obstetrics and Gynaecology
Reproductive Medicine

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10.1016/j.fertnstert.2009.05.064

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title = "Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells",

abstract = "We aimed to investigate the effects of LH and FSH on the gene expression of the platelet-derived growth factor (PDGF) gene family in human granulosa-luteal cells. We found that LH significantly increased PDGF-D messenger RNA (mRNA) expression but suppressed PDGF-B and PDGF-C mRNA in human granulosa-luteal cells, and FSH also increases PDGF-D gene expression, but to a lesser extent.",

author = "Hwu, \{Yuh Ming\} and Li, \{Sheng Hsiang\} and Lee, \{Robert Kuo kuang\} and Lin, \{Ming Huei\} and Tsai, \{Yu Hui\} and Tian-Shun Tsai",

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AU - Hwu, Yuh Ming

AU - Li, Sheng Hsiang

AU - Lee, Robert Kuo kuang

AU - Lin, Ming Huei

AU - Tsai, Yu Hui

AU - Tsai, Tian-Shun

PY - 2009/12

Y1 - 2009/12

N2 - We aimed to investigate the effects of LH and FSH on the gene expression of the platelet-derived growth factor (PDGF) gene family in human granulosa-luteal cells. We found that LH significantly increased PDGF-D messenger RNA (mRNA) expression but suppressed PDGF-B and PDGF-C mRNA in human granulosa-luteal cells, and FSH also increases PDGF-D gene expression, but to a lesser extent.

AB - We aimed to investigate the effects of LH and FSH on the gene expression of the platelet-derived growth factor (PDGF) gene family in human granulosa-luteal cells. We found that LH significantly increased PDGF-D messenger RNA (mRNA) expression but suppressed PDGF-B and PDGF-C mRNA in human granulosa-luteal cells, and FSH also increases PDGF-D gene expression, but to a lesser extent.

UR - https://www.scopus.com/pages/publications/70749104907

UR - https://www.scopus.com/pages/publications/70749104907#tab=citedBy

U2 - 10.1016/j.fertnstert.2009.05.064

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AN - SCOPUS:70749104907

SN - 0015-0282

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EP - 2068

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 6

ER -

Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells

Abstract

ASJC Scopus subject areas

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