Low- and high-density lipoprotein cholesterol goal attainment in dyslipidemic women: The Lipid Treatment Assessment Project (L-TAP) 2

Raul D. Santos; David D. Waters; Lisa Tarasenko; Michael Messig; J. Wouter Jukema; Jean Ferrières; Juan Verdejo; Cheng Wen Chiang

doi:10.1016/j.ahj.2009.08.009

Low- and high-density lipoprotein cholesterol goal attainment in dyslipidemic women: The Lipid Treatment Assessment Project (L-TAP) 2

Raul D. Santos
, David D. Waters
, Lisa Tarasenko
, Michael Messig
, J. Wouter Jukema
, Jean Ferrières
, Juan Verdejo
, Cheng Wen Chiang

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

Background: Differences between women and men have been documented for both diagnostic testing and treatment in cardiology. This analysis evaluates whether low-density lipoprotein cholesterol (LDL-C) success rates according to current guidelines and high-density lipoprotein cholesterol (HDL-C) levels differ by gender in the L-TAP 2 population. Methods: Patients aged ≥20 years with dyslipidemia on stable lipid-lowering therapy were assessed in 9 countries between September 2006 and April 2007. Low-density lipoprotein cholesterol goal attainment by cardiovascular risk level and region and determinants of low HDL-C were compared between genders. Results: Of 9,955 patients (45.3% women) evaluated, women had a significantly lower overall LDL-C success rate than men (71.5% vs 73.7%, P = .014), due entirely to the difference in the high-risk/coronary heart disease (CHD) group (LDL-C goal

Original language	English
Pages (from-to)	860-866
Number of pages	7
Journal	American Heart Journal
Volume	158
Issue number	5
DOIs	https://doi.org/10.1016/j.ahj.2009.08.009
Publication status	Published - Nov 2009
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

General Medicine
Cardiology and Cardiovascular Medicine

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10.1016/j.ahj.2009.08.009

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@article{56d0200a25b544bca49f4926d629472f,

title = "Low- and high-density lipoprotein cholesterol goal attainment in dyslipidemic women: The Lipid Treatment Assessment Project (L-TAP) 2",

abstract = "Background: Differences between women and men have been documented for both diagnostic testing and treatment in cardiology. This analysis evaluates whether low-density lipoprotein cholesterol (LDL-C) success rates according to current guidelines and high-density lipoprotein cholesterol (HDL-C) levels differ by gender in the L-TAP 2 population. Methods: Patients aged ≥20 years with dyslipidemia on stable lipid-lowering therapy were assessed in 9 countries between September 2006 and April 2007. Low-density lipoprotein cholesterol goal attainment by cardiovascular risk level and region and determinants of low HDL-C were compared between genders. Results: Of 9,955 patients (45.3\% women) evaluated, women had a significantly lower overall LDL-C success rate than men (71.5\% vs 73.7\%, P = .014), due entirely to the difference in the high-risk/coronary heart disease (CHD) group (LDL-C goal ",

author = "Santos, \{Raul D.\} and Waters, \{David D.\} and Lisa Tarasenko and Michael Messig and Jukema, \{J. Wouter\} and Jean Ferri{\`e}res and Juan Verdejo and Chiang, \{Cheng Wen\}",

note = "Funding Information: The L-TAP 2 study was funded by Pfizer Inc (New York, NY). The authors are solely responsible for the design and conduct of this study, all study analyses, and the drafting and editing of the paper and its final contents. Assistance in manuscript formatting and preparation of figures was provided by UBC Scientific Solutions Ltd. and funded by Pfizer Inc. ",

year = "2009",

month = nov,

doi = "10.1016/j.ahj.2009.08.009",

language = "English",

volume = "158",

pages = "860--866",

journal = "American Heart Journal",

issn = "0002-8703",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Low- and high-density lipoprotein cholesterol goal attainment in dyslipidemic women

T2 - The Lipid Treatment Assessment Project (L-TAP) 2

AU - Santos, Raul D.

AU - Waters, David D.

AU - Tarasenko, Lisa

AU - Messig, Michael

AU - Jukema, J. Wouter

AU - Ferrières, Jean

AU - Verdejo, Juan

AU - Chiang, Cheng Wen

N1 - Funding Information: The L-TAP 2 study was funded by Pfizer Inc (New York, NY). The authors are solely responsible for the design and conduct of this study, all study analyses, and the drafting and editing of the paper and its final contents. Assistance in manuscript formatting and preparation of figures was provided by UBC Scientific Solutions Ltd. and funded by Pfizer Inc.

PY - 2009/11

Y1 - 2009/11

N2 - Background: Differences between women and men have been documented for both diagnostic testing and treatment in cardiology. This analysis evaluates whether low-density lipoprotein cholesterol (LDL-C) success rates according to current guidelines and high-density lipoprotein cholesterol (HDL-C) levels differ by gender in the L-TAP 2 population. Methods: Patients aged ≥20 years with dyslipidemia on stable lipid-lowering therapy were assessed in 9 countries between September 2006 and April 2007. Low-density lipoprotein cholesterol goal attainment by cardiovascular risk level and region and determinants of low HDL-C were compared between genders. Results: Of 9,955 patients (45.3% women) evaluated, women had a significantly lower overall LDL-C success rate than men (71.5% vs 73.7%, P = .014), due entirely to the difference in the high-risk/coronary heart disease (CHD) group (LDL-C goal

AB - Background: Differences between women and men have been documented for both diagnostic testing and treatment in cardiology. This analysis evaluates whether low-density lipoprotein cholesterol (LDL-C) success rates according to current guidelines and high-density lipoprotein cholesterol (HDL-C) levels differ by gender in the L-TAP 2 population. Methods: Patients aged ≥20 years with dyslipidemia on stable lipid-lowering therapy were assessed in 9 countries between September 2006 and April 2007. Low-density lipoprotein cholesterol goal attainment by cardiovascular risk level and region and determinants of low HDL-C were compared between genders. Results: Of 9,955 patients (45.3% women) evaluated, women had a significantly lower overall LDL-C success rate than men (71.5% vs 73.7%, P = .014), due entirely to the difference in the high-risk/coronary heart disease (CHD) group (LDL-C goal

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DO - 10.1016/j.ahj.2009.08.009

M3 - Article

C2 - 19853709

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VL - 158

SP - 860

EP - 866

JO - American Heart Journal

JF - American Heart Journal

IS - 5

ER -

Low- and high-density lipoprotein cholesterol goal attainment in dyslipidemic women: The Lipid Treatment Assessment Project (L-TAP) 2

Abstract

UN SDGs

ASJC Scopus subject areas

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