Abstract
The objective of this study was to evaluate the expression of epithelial membrane protein-2 (EMP2) and its clinicopathological associations in patients with gallbladder carcinoma (GBC). A retrospective population-based cohort study was performed based on a biobank from 1986 to 2005. Biopsies of 164 GBC patients without initial distant metastasis were collected during surgical intervention. Immunoexpressions of EMP2 and Ki-67 were analyzed and the outcomes were correlated with clinicopathological features and patient survival. Results indicated that loss of EMP2 expression (50%) was correlated with female patients ( p=0.037), advanced primary tumor ( p
Original language | English |
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Pages (from-to) | 31-38 |
Number of pages | 8 |
Journal | Biomarkers and Genomic Medicine |
Volume | 5 |
Issue number | 1-2 |
DOIs | |
Publication status | Published - 2013 |
Externally published | Yes |
Keywords
- Epithelial membrane protein-2
- Gallbladder carcinoma
- Survival
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biomedical Engineering
- Medicine(all)
- Drug Discovery