Long-term opioid treatment in Behçet's syndrome with intractable abdominal pain - A case report

Hsiang Chien Tseng, Yeong-Ray Wen, Jui Yuan Chen, Chia Ling Lee, Gong Jhe Wu, Yi Chang, Shan Chung Swei

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Opioids are the most potent and effective analgesics available for treating acute and chronic cancer pain, but its usefulness in treating non-cancer chronic pain is still controversial. We report a 23-year-old male suffering from Behçet's disease with persistent excruciating abdominal pain. Oral non-steroid anti-inflammation analgesics and milder opioids (codeine and tramadol) failed to relieve the pain. His excruciating abdominal pain resulting from ulcerative viscera aggravated with repeated gastrointestinal tract surgeries. Intravenous morphine given through patient-controlled analgesia (PCA) could effectively reduce his pain with minimal side effects. No sign of physical or psychological dependence was observed during the period of opiate administration, and no withdrawal phenomenon was found as the dosage was tapered. During the total treatment course of 213 days, the daily dose of morphine once surged up to 259.2 mg. The long-term opioid treatment and its possible effects are, herein, discussed.

Original languageEnglish
Pages (from-to)143-148
Number of pages6
JournalActa Anaesthesiologica Sinica
Issue number3
Publication statusPublished - Sept 2002
Externally publishedYes


  • Abdominal pain
  • Analgesics, opioid-related disorders
  • Behçet's syndrome

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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