Large cell neuroendocrine carcinoma of the uterine cervix associated with adenocarcinoma

Ma Lee Ko, Cherng Jye Jeng, Shih Hung Huang, Jenta Shen, Su Chee Chen, Chii Ruey Tzeng

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Objective: Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive cervical neoplasm. In the present study, we present a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma with coexisting adenocarcinoma. Case Report: A 45-year-old G2 P0 presented with vaginal bleeding for 7 months. On pelvic examination, a polypoid mass of the cervix was discovered. Biopsy of the lesion revealed large cell neuroendocrine carcinoma of the cervix. The patient underwent a radical hysterectomy, and then received concurrent chemotherapy and radiation therapy. She has remained disease free until the time of this writing. Conclusion: Patients with LCNEC of the cervix have had poor prognoses; hence aggressive multimodality treatment is recommended.

Original languageEnglish
Pages (from-to)68-70
Number of pages3
JournalTaiwanese Journal of Obstetrics and Gynecology
Issue number1
Publication statusPublished - Mar 2007


  • Adenocarcinoma of the cervix
  • Large cell neuroendocrine carcinoma of the cervix

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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