@inproceedings{bb7448d9cd8446739f9b613afb2a80b8,
title = "Label-free nanofluidic preconcentration with multi-operational modes by loop currents monitoring for biological application",
abstract = "A novel method, {"}loop currents monitoring{"}, was proposed for interpreting the onset of preconcentration mechanism and the behaviors of a preconcentrated plug of a nanofluidic preconcentrator without fluorescent labeling. Three operational modes of preconcentrated plugs during the preconcentration process were explained by loop currents of the chip and flow profiles including electroosmotic flow (EOF) and nanochannel-induced backflow (EOF of the second kind). It is demonstrated that our nanofluidic preconcentrator has the capability to precisely control and rapidly preconcentrate label-free proteins.",
keywords = "Electroosmotic flow, Ion concentration polarization (ICP), Label-free nanofluidic sample preconcentration, Loop currents monitoring, Permselective nanochannel, Space charge region",
author = "Chung, {Pei Shan} and Yen-Lin Liu and Liao, {K. P.} and Fan, {Y. J.} and Sung, {K. B.} and Sheen, {Horn Jiunn} and Tian, {Wei Cheng}",
year = "2013",
language = "English",
isbn = "9781632666246",
volume = "3",
series = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
publisher = "Chemical and Biological Microsystems Society",
pages = "1403--1405",
booktitle = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
note = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 ; Conference date: 27-10-2013 Through 31-10-2013",
}