Kappa Light-Chain Multiple Myeloma with Myelomatous Pleural Effusion a Case Report and Review of the Literature

余 福九(Fu-Chiu Yu), 張 俊彥(Jang-Yang Chang), 黃 旭輝(Shiu-Hui Hwang), 李 恒昇(Herng-Sheng Lee), 黃 偉修(Wei-Hsiu Hwang)

Research output: Contribution to journalArticlepeer-review

Abstract

臨床上造成肋膜積水的原因有許多,例如:心臟衰竭、腎病症候群、肝硬化及腫瘤等。在多發性骨髓瘤者,肋膜積水中出現多發性骨髓瘤細胞,非常少見,此時對於化學治療的效果及預後皆不佳。報告一位kappa輕鏈多發性骨髓瘤合併肋膜積水的病例,經由骨髓病理切片及肋膜積水細胞的免疫化學染色檢查,均發現kappa輕鏈多發性骨髓瘤細胞,並討論有關多發性骨髓瘤肋膜積水的細胞學診斷及影響預後的因素。The occurrence of myelomatous pleural effusion in patients with multiple myeloma is extremely rare. Here we report a case of kappa light-chain multiple myeloma with myelomatous pleural effusion, which was confirmed by Wright-Geimsa stain and immunocytochemical studies of sediments of pleural effusion. The related literature about the cytologic diagnosis and the prognostic factors of myelomatous pleural effusion are also reviewed.
Original languageEnglish
Pages (from-to)49-55
Number of pages7
JournalJournal of Medical Sciences
Volume15
Issue number1
Publication statusPublished - Aug 1994
Externally publishedYes

Keywords

  • 多種性骨髓瘤
  • 肋膜積水
  • multiple myeloma
  • myelomatous pleural effusion

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