TY - JOUR
T1 - Jugular venous hemodynamic changes with aging
AU - Chung, Chih Ping
AU - Lin, Ya J.
AU - Chao, A. Ching
AU - Lin, Shing Jong
AU - Chen, Yen Y.
AU - Wang, Yuh J.
AU - Hu, Han H.
N1 - Funding Information:
This work was supported by a National Science Council Research grant ( NSC95-2314-B075-041-MY3 , H-H H).
PY - 2010/11/1
Y1 - 2010/11/1
N2 - Cerebral venous outflow insufficiency via the internal jugular vein (IJV) is associated with several neurological disorders. However, a normal reference set of IJV hemodynamic parameters derived from a large, healthy population over a wide range of age has, until now, been lacking. Color-coded duplex sonography was performed on the IJVs of 349 subjects (55.60 ± 17.49,16 to 89 y; 167 M/182 F). With increasing age, increased lumen area and decreased time-averaged mean velocity of bilateral IJV and a decreased proportion of total flow volume, drainage in the left IJV were found. The frequency of left jugular venous reflux (JVR) also increased with aging. We report IJV hemodynamic parameters across a large population, which could be used as a normal reference for clinical and research purposes. Furthermore, we found a decreased proportion of venous drainage, increased JVR prevalence, dilated lumen and slowed flow velocity in the left IJV, all of which suggest increased left IJV outflow impedance with aging.
AB - Cerebral venous outflow insufficiency via the internal jugular vein (IJV) is associated with several neurological disorders. However, a normal reference set of IJV hemodynamic parameters derived from a large, healthy population over a wide range of age has, until now, been lacking. Color-coded duplex sonography was performed on the IJVs of 349 subjects (55.60 ± 17.49,16 to 89 y; 167 M/182 F). With increasing age, increased lumen area and decreased time-averaged mean velocity of bilateral IJV and a decreased proportion of total flow volume, drainage in the left IJV were found. The frequency of left jugular venous reflux (JVR) also increased with aging. We report IJV hemodynamic parameters across a large population, which could be used as a normal reference for clinical and research purposes. Furthermore, we found a decreased proportion of venous drainage, increased JVR prevalence, dilated lumen and slowed flow velocity in the left IJV, all of which suggest increased left IJV outflow impedance with aging.
KW - Aging
KW - Cerebral venous outflow insufficiency
KW - Jugular venous reflux
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U2 - 10.1016/j.ultrasmedbio.2010.07.006
DO - 10.1016/j.ultrasmedbio.2010.07.006
M3 - Article
C2 - 20800950
AN - SCOPUS:77958150473
SN - 0301-5629
VL - 36
SP - 1776
EP - 1782
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 11
ER -