Jugular venous hemodynamic changes with aging

Chih Ping Chung, Ya J. Lin, A. Ching Chao, Shing Jong Lin, Yen Y. Chen, Yuh J. Wang, Han H. Hu

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)


Cerebral venous outflow insufficiency via the internal jugular vein (IJV) is associated with several neurological disorders. However, a normal reference set of IJV hemodynamic parameters derived from a large, healthy population over a wide range of age has, until now, been lacking. Color-coded duplex sonography was performed on the IJVs of 349 subjects (55.60 ± 17.49,16 to 89 y; 167 M/182 F). With increasing age, increased lumen area and decreased time-averaged mean velocity of bilateral IJV and a decreased proportion of total flow volume, drainage in the left IJV were found. The frequency of left jugular venous reflux (JVR) also increased with aging. We report IJV hemodynamic parameters across a large population, which could be used as a normal reference for clinical and research purposes. Furthermore, we found a decreased proportion of venous drainage, increased JVR prevalence, dilated lumen and slowed flow velocity in the left IJV, all of which suggest increased left IJV outflow impedance with aging.

Original languageEnglish
Pages (from-to)1776-1782
Number of pages7
JournalUltrasound in Medicine and Biology
Issue number11
Publication statusPublished - Nov 1 2010
Externally publishedYes


  • Aging
  • Cerebral venous outflow insufficiency
  • Jugular venous reflux

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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