TY - JOUR
T1 - Intrinsic neural timescales relate to the dynamics of infraslow neural waves
AU - Ao, Yujia
AU - Catal, Yasir
AU - Lechner, Stephan
AU - Hua, Jingyu
AU - Northoff, Georg
N1 - Publisher Copyright:
© 2023
PY - 2024/1
Y1 - 2024/1
N2 - The human brain is a highly dynamic organ that operates across a variety of timescales, the intrinsic neural timescales (INT). In addition to the INT, the neural waves featured by its phase-related processes including their cycles with peak/trough and rise/fall play a key role in shaping the brain's neural activity. However, the relationship between the brain's ongoing wave dynamics and INT remains yet unclear. In this study, we utilized functional magnetic resonance imaging (fMRI) rest and task data from the Human Connectome Project (HCP) to investigate the relationship of infraslow wave dynamics [as measured in terms of speed by changes in its peak frequency (PF)] with INT. Our findings reveal that: (i) the speed of phase dynamics (PF) is associated with distinct parts of the ongoing phase cycles, namely higher PF in peak/trough and lower PF in rise/fall; (ii) there exists a negative correlation between phase dynamics (PF) and INT such that slower PF relates to longer INT; (iii) exposure to a movie alters both PF and INT across the different phase cycles, yet their negative correlation remains intact. Collectively, our results demonstrate that INT relates to infraslow phase dynamics during both rest and task states.
AB - The human brain is a highly dynamic organ that operates across a variety of timescales, the intrinsic neural timescales (INT). In addition to the INT, the neural waves featured by its phase-related processes including their cycles with peak/trough and rise/fall play a key role in shaping the brain's neural activity. However, the relationship between the brain's ongoing wave dynamics and INT remains yet unclear. In this study, we utilized functional magnetic resonance imaging (fMRI) rest and task data from the Human Connectome Project (HCP) to investigate the relationship of infraslow wave dynamics [as measured in terms of speed by changes in its peak frequency (PF)] with INT. Our findings reveal that: (i) the speed of phase dynamics (PF) is associated with distinct parts of the ongoing phase cycles, namely higher PF in peak/trough and lower PF in rise/fall; (ii) there exists a negative correlation between phase dynamics (PF) and INT such that slower PF relates to longer INT; (iii) exposure to a movie alters both PF and INT across the different phase cycles, yet their negative correlation remains intact. Collectively, our results demonstrate that INT relates to infraslow phase dynamics during both rest and task states.
KW - Functional magnetic resonance imaging
KW - Infraslow neural waves
KW - Intrinsic neural timescales
KW - Temporal input processing
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U2 - 10.1016/j.neuroimage.2023.120482
DO - 10.1016/j.neuroimage.2023.120482
M3 - Article
C2 - 38043840
AN - SCOPUS:85179472790
SN - 1053-8119
VL - 285
JO - NeuroImage
JF - NeuroImage
M1 - 120482
ER -