Intrahepatic cholangiocarcinoma in hepatolithiasis: A frequently overlooked disease

Shyr‐Ming ‐M Sheen‐Chen, Fong‐Fu ‐F Chou, Hock‐Liew ‐L Eng

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80 Citations (Scopus)


Five cases of intrahepatic cholangiocarcinoma were found among 101 cases of hepatolithiasis. There was no definite sign of cholangiocarcinoma in ERCP and image studies of four cases. The possibility of the existence of occult cholangiocarcinoma should be kept in mind, especially when unusual presentations, such as body weight loss, anemia, palpable abdominal mass, and intractable pain, appear. An intraoperative frozen‐section examination should be considered under the following circumstances: (1) whitish nodular mass over liver, (2) mucinous substance within bile duct, and (3) enlarged, firm lymph nodes clustered along the hepatic arteries and/or celiac arteries.

Original languageEnglish
Pages (from-to)131-135
Number of pages5
JournalJournal of Surgical Oncology
Issue number2
Publication statusPublished - Jun 1991
Externally publishedYes


  • abdominal ultrasonography
  • choledochotomy
  • endoscopic retrograde cholangiopancreatography (ERCP)

ASJC Scopus subject areas

  • Surgery
  • Oncology


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