Intelligent Bio-Impedance System for Personalized Continuous Blood Pressure Measurement

Ting Wei Wang, Jhen Yang Syu, Hsiao Wei Chu, Yen Ling Sung, Lin Chou, Endian Escott, Olivia Escott, Ting Tse Lin, Shien Fong Lin

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Continuous blood pressure (BP) measurement is crucial for long-term cardiovascular monitoring, especially for prompt hypertension detection. However, most of the continuous BP measurements rely on the pulse transit time (PTT) from multiple-channel physiological acquisition systems that impede wearable applications. Recently, wearable and smart health electronics have become significant for next-generation personalized healthcare progress. This study proposes an intelligent single-channel bio-impedance system for personalized BP monitoring. Compared to the PTT-based methods, the proposed sensing configuration greatly reduces the hardware complexity, which is beneficial for wearable applications. Most of all, the proposed system can extract the significant BP features hidden from the measured bio-impedance signals by an ultra-lightweight AI algorithm, implemented to further establish a tailored BP model for personalized healthcare. In the human trial, the proposed system demonstrates the BP accuracy in terms of the mean error (ME) and the mean absolute error (MAE) within 1.7 ± 3.4 mmHg and 2.7 ± 2.6 mmHg, respectively, which agrees with the criteria of the Association for the Advancement of Medical Instrumentation (AAMI). In conclusion, this work presents a proof-of-concept for an AI-based single-channel bio-impedance BP system. The new wearable smart system is expected to accelerate the artificial intelligence of things (AIoT) technology for personalized BP healthcare in the future.

Original languageEnglish
Article number150
Issue number3
Publication statusPublished - Mar 2022
Externally publishedYes


  • Artificial intelligence
  • Bio-impedance measurement
  • Continuous blood pressure measurement
  • Impedance plethysmography
  • Intelligent system

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biotechnology
  • Biomedical Engineering
  • Instrumentation
  • Engineering (miscellaneous)
  • Clinical Biochemistry


Dive into the research topics of 'Intelligent Bio-Impedance System for Personalized Continuous Blood Pressure Measurement'. Together they form a unique fingerprint.

Cite this