Injectable Calcium Sulfate as a Bone Substiute In Rabbits

陳 志宏(Chih-Hong Chen), Chih-Hwa Chen, 潘 宏維(Horng-Wei Pan), 葉 晉志(Chin-Chih Yen), 薛 文景(Wen-Ching Say), 陳 文哲(Wen-Jer Chen), 施 俊雄(Chou-Hsiung Shih)

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This study is to investigate the physical proper properties of an injectable form calcium sulfate and to evaluate its osteoconductive ability in a rabbit model. The particle size was 2200±90 nm. The setting time of liquid calcium sulfate was 17.0±0.5 min. The mean compressive and bending strengths were 44.9±9.59 and 14.06±2.06 Mpa, respectively. In rabbits, a liquid calcium sulfate was injected into a 5 x 10 mm cylindrical hole at the medial femoral condyle. Complete resorption of the injectable calcium sulfate occurred by 8weeks with a ring of remodeling cancellous bone formed in the peripheral region. By 12 weeks, the calcium sulfate in the bone defect was completely absorbed and replaced by regenerated trabecular bone.
Translated title of the contribution以可注射性的硫酸鈣作為骨取代物之兔子動物實驗
Original languageEnglish
Pages (from-to)28-31
Number of pages4
JournalJournal of Orthopedic Surgery Taiwan
Issue number1
Publication statusPublished - 2002


  • calcuium sulfate
  • bone substitute
  • osteoconducton


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