Induction of connective tissue growth factor expression by hypoxia in human lung fibroblasts via the MEKK1/MEK1/ERK1/GLI-1/GLI-2 and AP-1 pathways

Medicine & Life Sciences

• MAP Kinase Kinase Kinase 1 100%
• Connective Tissue Growth Factor 79%
• Transcription Factor AP-1 66%
• Hypoxia 47%
• Fibroblasts 44%
• Small Interfering RNA 39%
• Lung 32%
• Cell Hypoxia 16%
• U 0126 16%
• Luciferases 12%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 10%
• Phosphorylation 8%
• p38 Mitogen-Activated Protein Kinases 8%
• Collagen 6%
• SB 203580 5%
• Idiopathic Pulmonary Fibrosis 5%
• Pulmonary Fibrosis 4%
• Chromatin Immunoprecipitation 4%
• Mitogen-Activated Protein Kinase Kinases 4%
• Genetic Promoter Regions 4%
• Smooth Muscle 3%
• Actins 3%
• Cell Line 2%
• Mutation 2%