Induction of connective tissue growth factor expression by hypoxia in human lung fibroblasts via the MEKK1/MEK1/ERK1/GLI-1/GLI-2 and AP-1 pathways

Neuroscience

• Fibroblast 100%
• AP-1 Transcription Factor 100%
• Mitogen Activated Protein Kinase 3 100%
• Kinase 100%
• CTGF 100%
• Small Interfering RNA 91%
• Luciferase 25%
• U0126 25%
• Mitogen-Activated Protein Kinase 16%
• Pulmonary Fibrosis 16%
• Promoter Region 8%
• Cell Line 8%
• Complex Formation 8%
• Smooth Muscle Actin 8%
• Mitogen-Activated Protein Kinase Kinase 8%
• Immunoprecipitation 8%
• MEK Inhibitor 8%

Biochemistry, Genetics and Molecular Biology

• Fibroblast 100%
• AP-1 Transcription Factor 100%
• Kinase 100%
• Phosphotransferase 100%
• Connective Tissue Growth Factor 100%
• Small Interfering RNA 91%
• U0126 25%
• Luciferase 25%
• P38 Mitogen-Activated Protein Kinases 16%
• Promoter Region 8%
• Complex Formation 8%
• Chromatin Immunoprecipitation 8%
• WI-38 8%
• Actin 8%
• Mitogen-Activated Protein Kinase Kinase 8%
• MEK Inhibitor 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Hypoxia 100%
• Phosphotransferase 100%
• Mitogen Activated Protein Kinase 3 100%
• Transcription Factor AP 1 100%
• Connective Tissue Growth Factor 100%
• Small Interfering RNA 61%
• 1,4 Diamino 1,4 Bis(2 Aminophenylthio) 2,3 Dicyanobutadiene 16%
• Luciferase 16%
• 2 (2 Amino 3 Methoxyphenyl)chromone 11%
• Mitogen Activated Protein Kinase Kinase 5%
• SB 203580 5%
• Chromatin Immunoprecipitation 5%
• Fibrosing Alveolitis 5%
• Lung Fibrosis 5%
• Smooth Muscle Actin 5%
• Mitogen Activated Protein Kinase Kinase Inhibitor 5%