Abstract
This study was aimed at examining the effects of glucosinolate derivatives including phenylethyl isothiocyanate (PEITC), benzyl isothiocyanate (BITC), and indole-3-carbinol (I3C), on the induction of apoptosis in human non-small cell lung carcinoma A549 cells. The results indicated that all tested compounds inhibited the growth of A549 cells in a concentration-dependent manner. Flow cytometric analyses and annexin V staining showed that induction of apoptosis occurred at low concentrations of PEITC and BITC (â
| Original language | English |
|---|---|
| Pages (from-to) | 1711-1718 |
| Number of pages | 8 |
| Journal | Food and Chemical Toxicology |
| Volume | 42 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 2004 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Apoptosis
- Indole-3-carbinol
- Isothiocyanate
- Lung adenocarcinoma A549 cells
- P21
- P53
ASJC Scopus subject areas
- Food Science
- Toxicology
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