Indoor Air quality and cardiovascular effects in the Taiwanese general population: Generalized additive mixed models analysis

Wan Yu Chuang, Lian Yu Lin, Kai-Jen Chuang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

While the effects of air pollution exposure on cardiovascular morbidity and mortality are well documented, the underlying mechanisms linking indoor air quality to cardiovascular diseases are largely unknown. In order to investigate changes in blood pressure (BP) and heart rate (HR) associated with changes in exposure to indoor air pollution, we conducted nonlinear time series analysis of BP, HR and indoor air quality from the survey of health and living status of the general population in Taiwan. Associations of daily averaged indoor air pollutants [particulate matter with aerodynamic diameters <10 μm (PM 10), particulate matter with aerodynamic diameters <2.5 μm (PM2.5), total volatile compounds (VOCs) and carbon dioxide (CO 2)] with systolic BP (SBP), diastolic BP (DBP) and HR were explored by applying generalized additive mixed models. After controlling for potential confounders, we observed that increased hourly averaged indoor PM2.5 was associated with elevated SBP, DBP and HR. Associations of increased hourly averaged total VOCs with elevated SBP and HR were also observed. We concluded that changes in BP and HR are associated with exposure to indoor air pollutants in the Taiwanese general population.

Original languageEnglish
Title of host publicationProceedings of the World Congress on Engineering 2013, WCE 2013
Pages295-298
Number of pages4
Publication statusPublished - 2013
Event2013 World Congress on Engineering, WCE 2013 - London, United Kingdom
Duration: Jul 3 2013Jul 5 2013

Publication series

NameLecture Notes in Engineering and Computer Science
Volume1 LNECS
ISSN (Print)2078-0958

Other

Other2013 World Congress on Engineering, WCE 2013
Country/TerritoryUnited Kingdom
CityLondon
Period7/3/137/5/13

Keywords

  • Blood pressure
  • Epidemiology
  • Generalized additive model
  • Indoor air pollution
  • Inflammation

ASJC Scopus subject areas

  • Computer Science (miscellaneous)

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