Increased risk of stroke after trigeminal neuralgia-a population-based follow-up study

Shin Liang Pan; Li Sheng Chen; Ming Fang Yen; Yueh Hsia Chiu; Hsiu Hsi Chen

doi:10.1177/0333102411405225

Increased risk of stroke after trigeminal neuralgia-a population-based follow-up study

Shin Liang Pan, Li Sheng Chen, Ming Fang Yen, Yueh Hsia Chiu, Hsiu Hsi Chen

Research output: Contribution to journal › Review article › peer-review

16 Citations (Scopus)

Abstract

Background: There are no reports on the risk of stroke after trigeminal neuralgia (TN). The aim of this population-based follow-up study was to investigate whether the occurrence of TN is associated with a higher risk of developing stroke.Methods: A total of 1453 people with at least three ambulatory visits in 2001 with the principal diagnosis of TN were enrolled in the TN cohort. The non-TN cohort consisted of 5812 age- and sex-matched, randomly sampled subjects without TN. The 2-year stroke-free survival rate between the two groups was compared using the Kaplan-Meier method. The Cox proportional hazards regression model was used to estimate the hazard ratio of stroke after adjustment for demographic and clinical covariates.Results: In the TN cohort, 73 patients developed stroke during follow-up, while in the non-TN cohort, 157 subjects suffered a stroke. The crude hazard ratio of stroke for the subjects with TN was 1.86 (95% CI, 1.41-2.45; p-

Original language	English
Pages (from-to)	937-942
Number of pages	6
Journal	Cephalalgia
Volume	31
Issue number	8
DOIs	https://doi.org/10.1177/0333102411405225
Publication status	Published - Jun 2011

Keywords

Trigeminal neuralgia
cerebrovascular disease
risk factors
stroke

ASJC Scopus subject areas

Clinical Neurology

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10.1177/0333102411405225

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title = "Increased risk of stroke after trigeminal neuralgia-a population-based follow-up study",

abstract = "Background: There are no reports on the risk of stroke after trigeminal neuralgia (TN). The aim of this population-based follow-up study was to investigate whether the occurrence of TN is associated with a higher risk of developing stroke.Methods: A total of 1453 people with at least three ambulatory visits in 2001 with the principal diagnosis of TN were enrolled in the TN cohort. The non-TN cohort consisted of 5812 age- and sex-matched, randomly sampled subjects without TN. The 2-year stroke-free survival rate between the two groups was compared using the Kaplan-Meier method. The Cox proportional hazards regression model was used to estimate the hazard ratio of stroke after adjustment for demographic and clinical covariates.Results: In the TN cohort, 73 patients developed stroke during follow-up, while in the non-TN cohort, 157 subjects suffered a stroke. The crude hazard ratio of stroke for the subjects with TN was 1.86 (95% CI, 1.41-2.45; p-",

keywords = "Trigeminal neuralgia, cerebrovascular disease, risk factors, stroke",

author = "Pan, {Shin Liang} and Chen, {Li Sheng} and Yen, {Ming Fang} and Chiu, {Yueh Hsia} and Chen, {Hsiu Hsi}",

year = "2011",

month = jun,

doi = "10.1177/0333102411405225",

language = "English",

volume = "31",

pages = "937--942",

journal = "Cephalalgia",

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T1 - Increased risk of stroke after trigeminal neuralgia-a population-based follow-up study

AU - Pan, Shin Liang

AU - Chen, Li Sheng

AU - Yen, Ming Fang

AU - Chiu, Yueh Hsia

AU - Chen, Hsiu Hsi

PY - 2011/6

Y1 - 2011/6

N2 - Background: There are no reports on the risk of stroke after trigeminal neuralgia (TN). The aim of this population-based follow-up study was to investigate whether the occurrence of TN is associated with a higher risk of developing stroke.Methods: A total of 1453 people with at least three ambulatory visits in 2001 with the principal diagnosis of TN were enrolled in the TN cohort. The non-TN cohort consisted of 5812 age- and sex-matched, randomly sampled subjects without TN. The 2-year stroke-free survival rate between the two groups was compared using the Kaplan-Meier method. The Cox proportional hazards regression model was used to estimate the hazard ratio of stroke after adjustment for demographic and clinical covariates.Results: In the TN cohort, 73 patients developed stroke during follow-up, while in the non-TN cohort, 157 subjects suffered a stroke. The crude hazard ratio of stroke for the subjects with TN was 1.86 (95% CI, 1.41-2.45; p-

AB - Background: There are no reports on the risk of stroke after trigeminal neuralgia (TN). The aim of this population-based follow-up study was to investigate whether the occurrence of TN is associated with a higher risk of developing stroke.Methods: A total of 1453 people with at least three ambulatory visits in 2001 with the principal diagnosis of TN were enrolled in the TN cohort. The non-TN cohort consisted of 5812 age- and sex-matched, randomly sampled subjects without TN. The 2-year stroke-free survival rate between the two groups was compared using the Kaplan-Meier method. The Cox proportional hazards regression model was used to estimate the hazard ratio of stroke after adjustment for demographic and clinical covariates.Results: In the TN cohort, 73 patients developed stroke during follow-up, while in the non-TN cohort, 157 subjects suffered a stroke. The crude hazard ratio of stroke for the subjects with TN was 1.86 (95% CI, 1.41-2.45; p-

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KW - cerebrovascular disease

KW - risk factors

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Increased risk of stroke after trigeminal neuralgia-a population-based follow-up study

Abstract

Keywords

ASJC Scopus subject areas

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