Abstract
The ability to promote new bone formation of poor crystalline hydroxyapatite (PC-HA) based biphasic calcium phosphate (BCP) bone substitutes were investigated. Various ratios of porous PC-HA/β-TCP (70/30, 60/40, and 0/100) grafts were fabricated. SEM and XRD measurements were performed to study the morphology and crystalline structure. Cylindrical artificial bone defects (3×6 mm2) were produced in alveolar bone at premolars extraction site and then filled with sterilized bone grafts. Commercial MBCP® and unfilled empty defect served as control groups. At 8 weeks postoperation, samples were harvested from each artificial defect site for histological analysis. New bone formation of all the PC-HA/β-TCP groups was significantly greater than that of the empty control group (p
Original language | English |
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Pages (from-to) | 21-28 |
Number of pages | 8 |
Journal | Dental Materials Journal |
Volume | 30 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2011 |
Keywords
- β-tricalcium phosphate
- Biphasic calcium phosphate
- Bone graft
- Hydroxyapatite
- In vivo
ASJC Scopus subject areas
- Dentistry(all)
- Ceramics and Composites