In vitro evaluation of dentin tubule occlusion for novel calcium lactate phosphate (CLP) paste

Jen Chang Yang; Hsin Tai Hu; Sheng Yang Lee; Sung Chih Hsieh; Pei Chi Huang; Chen Feng Ma; Dian Yu Ji; Liang Yu Chang; Nai Chia Teng

doi:10.3390/ma10030228

In vitro evaluation of dentin tubule occlusion for novel calcium lactate phosphate (CLP) paste

Jen Chang Yang, Hsin Tai Hu, Sheng Yang Lee, Sung Chih Hsieh, Pei Chi Huang, Chen Feng Ma, Dian Yu Ji, Liang Yu Chang, Nai Chia Teng

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Introduction: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. Methods: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate® Pro-Relief™ paste, CLP paste, and double distilled water (ddH₂O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment. One-way ANOVA and post-hoc Tukey's test were used to determine whether there were any statistically significant differences in dentinal tubule diameter. Results: A significant decrease occurred in the mean tubule diameter for dentin disks treated with CLP paste. A decrease was observed from 3.52 ± 0.83 μm to 2.62 ± 0.42 μm right after treatment, further decreasing to 1.71 ± 0.45 μm after immersion in artificial saliva for 14 days (p < 0.05). Conclusions: The results suggest that the CLP based desensitizing paste has remineralization properties and provides instant and lasting effectiveness in dentinal tubule occlusion.

Original language	English
Article number	228
Journal	Materials
Volume	10
Issue number	3
DOIs	https://doi.org/10.3390/ma10030228
Publication status	Published - 2017

Keywords

Calcium lactate phosphate (CLP)
Dentin hypersensitivity
Desensitizing agent

ASJC Scopus subject areas

General Materials Science

Access to Document

10.3390/ma10030228

Cite this

@article{676ef1c01a544453b0b709ca3c7fe1d9,

title = "In vitro evaluation of dentin tubule occlusion for novel calcium lactate phosphate (CLP) paste",

abstract = "Introduction: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. Methods: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate{\textregistered} Pro-Relief{\texttrademark} paste, CLP paste, and double distilled water (ddH2O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment. One-way ANOVA and post-hoc Tukey's test were used to determine whether there were any statistically significant differences in dentinal tubule diameter. Results: A significant decrease occurred in the mean tubule diameter for dentin disks treated with CLP paste. A decrease was observed from 3.52 ± 0.83 μm to 2.62 ± 0.42 μm right after treatment, further decreasing to 1.71 ± 0.45 μm after immersion in artificial saliva for 14 days (p < 0.05). Conclusions: The results suggest that the CLP based desensitizing paste has remineralization properties and provides instant and lasting effectiveness in dentinal tubule occlusion.",

keywords = "Calcium lactate phosphate (CLP), Dentin hypersensitivity, Desensitizing agent",

author = "Yang, {Jen Chang} and Hu, {Hsin Tai} and Lee, {Sheng Yang} and Hsieh, {Sung Chih} and Huang, {Pei Chi} and Ma, {Chen Feng} and Ji, {Dian Yu} and Chang, {Liang Yu} and Teng, {Nai Chia}",

note = "Publisher Copyright: {\textcopyright} 2017 by the authors.",

year = "2017",

doi = "10.3390/ma10030228",

language = "English",

volume = "10",

journal = "Materials",

issn = "1996-1944",

publisher = "MDPI AG",

number = "3",

}

TY - JOUR

T1 - In vitro evaluation of dentin tubule occlusion for novel calcium lactate phosphate (CLP) paste

AU - Yang, Jen Chang

AU - Hu, Hsin Tai

AU - Lee, Sheng Yang

AU - Hsieh, Sung Chih

AU - Huang, Pei Chi

AU - Ma, Chen Feng

AU - Ji, Dian Yu

AU - Chang, Liang Yu

AU - Teng, Nai Chia

PY - 2017

Y1 - 2017

N2 - Introduction: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. Methods: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate® Pro-Relief™ paste, CLP paste, and double distilled water (ddH2O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment. One-way ANOVA and post-hoc Tukey's test were used to determine whether there were any statistically significant differences in dentinal tubule diameter. Results: A significant decrease occurred in the mean tubule diameter for dentin disks treated with CLP paste. A decrease was observed from 3.52 ± 0.83 μm to 2.62 ± 0.42 μm right after treatment, further decreasing to 1.71 ± 0.45 μm after immersion in artificial saliva for 14 days (p < 0.05). Conclusions: The results suggest that the CLP based desensitizing paste has remineralization properties and provides instant and lasting effectiveness in dentinal tubule occlusion.

AB - Introduction: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. Methods: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate® Pro-Relief™ paste, CLP paste, and double distilled water (ddH2O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment. One-way ANOVA and post-hoc Tukey's test were used to determine whether there were any statistically significant differences in dentinal tubule diameter. Results: A significant decrease occurred in the mean tubule diameter for dentin disks treated with CLP paste. A decrease was observed from 3.52 ± 0.83 μm to 2.62 ± 0.42 μm right after treatment, further decreasing to 1.71 ± 0.45 μm after immersion in artificial saliva for 14 days (p < 0.05). Conclusions: The results suggest that the CLP based desensitizing paste has remineralization properties and provides instant and lasting effectiveness in dentinal tubule occlusion.

KW - Calcium lactate phosphate (CLP)

KW - Dentin hypersensitivity

KW - Desensitizing agent

UR - http://www.scopus.com/inward/record.url?scp=85015063737&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85015063737&partnerID=8YFLogxK

U2 - 10.3390/ma10030228

DO - 10.3390/ma10030228

M3 - Article

AN - SCOPUS:85015063737

SN - 1996-1944

VL - 10

JO - Materials

JF - Materials

IS - 3

M1 - 228

ER -

In vitro evaluation of dentin tubule occlusion for novel calcium lactate phosphate (CLP) paste

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this