In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis complex isolated in Taiwan over 10 years

Tsi Shu Huang; Yung Ching Liu; Cheng Len Sy; Yao Shen Chen; Hui Zin Tu; Bao Chen

doi:10.1128/AAC.00414-07

In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis complex isolated in Taiwan over 10 years

Tsi Shu Huang, Yung Ching Liu, Cheng Len Sy, Yao Shen Chen, Hui Zin Tu, Bao Chen

Research output: Contribution to journal › Article › peer-review

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Abstract

Significant increases in the MIC₉₀S of linezolid in multidrug-resistant Mycobacterium tuberculosis isolates were seen between the baseline period of 2001 to 2003 (0.5 μg/ml) and 2004 (2 μg/ml). The MICs were 4 μg/ml in three strains. Both fluoroquinolones (except levofloxacin) and kanamycin were found to have statistically significant degrees of concordance with linezolid.

Original language	English
Pages (from-to)	2226-2227
Number of pages	2
Journal	Antimicrobial Agents and Chemotherapy
Volume	52
Issue number	6
DOIs	https://doi.org/10.1128/AAC.00414-07
Publication status	Published - Jun 2008
Externally published	Yes

ASJC Scopus subject areas

Pharmacology (medical)
Infectious Diseases
Pharmacology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/AAC.00414-07

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abstract = "Significant increases in the MIC90S of linezolid in multidrug-resistant Mycobacterium tuberculosis isolates were seen between the baseline period of 2001 to 2003 (0.5 μg/ml) and 2004 (2 μg/ml). The MICs were 4 μg/ml in three strains. Both fluoroquinolones (except levofloxacin) and kanamycin were found to have statistically significant degrees of concordance with linezolid.",

author = "Huang, {Tsi Shu} and Liu, {Yung Ching} and Sy, {Cheng Len} and Chen, {Yao Shen} and Tu, {Hui Zin} and Bao Chen",

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AU - Sy, Cheng Len

AU - Chen, Yao Shen

AU - Tu, Hui Zin

AU - Chen, Bao

PY - 2008/6

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AB - Significant increases in the MIC90S of linezolid in multidrug-resistant Mycobacterium tuberculosis isolates were seen between the baseline period of 2001 to 2003 (0.5 μg/ml) and 2004 (2 μg/ml). The MICs were 4 μg/ml in three strains. Both fluoroquinolones (except levofloxacin) and kanamycin were found to have statistically significant degrees of concordance with linezolid.

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In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis complex isolated in Taiwan over 10 years

Abstract

ASJC Scopus subject areas

UN SDGs

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