Purpose: 1) To determine the effect of a home-based walking exercise program on the sleep quality and quality of life of cancer patients, as well as 2) to determine if enhanced sleep quality was associated with improvement in quality of life over time. Methods: This is a prospective, longitudinal, two-armed, randomized clinical trial. Participants were recruited from oncology outpatient clinics in two university-based medical centers and were allocated to either usual care (n=35) or a home-based walking exercise intervention for 8 weeks (n=36). Measurements included the Taiwanese version of the Pittsburgh Sleep Quality Index, the Medical Outcomes Study Short Form-36, the Taiwanese Version Ratings of the Perceived Exertion Scale, and a walking exercise log. This study was analyzed on an intention-to-treat basis. Effects of the walking exercise program on sleep quality and quality of life were analyzed by the generalized estimating equation method. Results: Patients in the exercise group reported significant improvements in sleep quality (β=-3.54, p

Original languageEnglish
Pages (from-to)1329-1339
Number of pages11
JournalSupportive Care in Cancer
Issue number10
Publication statusPublished - Oct 2010


  • Cancer
  • Exercise
  • Home-based walking
  • Sleep
  • Sleep disturbances

ASJC Scopus subject areas

  • Oncology


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