Abstract
Accidental coincidence (randoms) is one of the factors that degrade the accuracy of positron emission tomography (PET). In contrast to widely-held beliefs, we have previously shown that randoms can significantly affect quantitative PET even after current hardware/software randoms correction is applied. In order to have better estimation of randoms for our Scanditronix scanner, we investigated the limitation of the vendor-provided randoms estimation and proposed a simple modification. Methods: Multiple short-frame data of a homogeneous circular cylinder were collected over 12 hours. Summed data were generated by summing up selected frames. Randoms of the summed data estimated by the vendor-provided method and our modified method were compared. Results: The vendor-provided randoms estimation did not work as well as the modified method when frame duration is much larger than the half-life of the radioactive agent used. Conclusion: Our minimal modification of the vendor-provided method significantly improves randoms estimation.
| Original language | English |
|---|---|
| Pages (from-to) | 121-123 |
| Number of pages | 3 |
| Journal | Journal of Medical and Biological Engineering |
| Volume | 24 |
| Issue number | 3 |
| Publication status | Published - Sept 2004 |
Keywords
- Algorithms
- Positron emission tomography
- Scintillation counting
ASJC Scopus subject areas
- Biophysics