Improved consistency in dosing anti-tuberculosis drugs in Taipei, Taiwan

Chen Yuan Chiang; Ming Chih Yu; Hsiu Chen Shih; Muh Yong Yen; Yu Ling Hsu; Shiang Lin Yang; Tao Ping Lin; Kuan Jen Bai

doi:10.1371/journal.pone.0044133

Improved consistency in dosing anti-tuberculosis drugs in Taipei, Taiwan

Chen Yuan Chiang, Ming Chih Yu, Hsiu Chen Shih, Muh Yong Yen, Yu Ling Hsu, Shiang Lin Yang, Tao Ping Lin, Kuan Jen Bai

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Background: It was reported that 35.5% of tuberculosis (TB) cases reported in 2003 in Taipei City had no recorded pre-treatment body weight and that among those who had, inconsistent dosing of anti-TB drugs was frequent. Taiwan Centers for Disease Control (CDC) have taken actions to strengthen dosing of anti-TB drugs among general practitioners. Prescribing practices of anti-TB drugs in Taipei City in 2007-2010 were investigated to assess whether interventions on dosing were effective. Methodology/Principal Findings: Lists of all notified culture positive TB cases in 2007-2010 were obtained from National TB Registry at Taiwan CDC. A medical audit of TB case management files was performed to collect pretreatment body weight and regimens prescribed at commencement of treatment. Dosages prescribed were compared with dosages recommended. The proportion of patients with recorded pre-treatment body weight was 64.5% in 2003, which increased to 96.5% in 2007-2010 (p

Original language	English
Article number	e44133
Journal	PLoS One
Volume	7
Issue number	8
DOIs	https://doi.org/10.1371/journal.pone.0044133
Publication status	Published - Aug 27 2012

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)
Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1371/journal.pone.0044133

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title = "Improved consistency in dosing anti-tuberculosis drugs in Taipei, Taiwan",

abstract = "Background: It was reported that 35.5% of tuberculosis (TB) cases reported in 2003 in Taipei City had no recorded pre-treatment body weight and that among those who had, inconsistent dosing of anti-TB drugs was frequent. Taiwan Centers for Disease Control (CDC) have taken actions to strengthen dosing of anti-TB drugs among general practitioners. Prescribing practices of anti-TB drugs in Taipei City in 2007-2010 were investigated to assess whether interventions on dosing were effective. Methodology/Principal Findings: Lists of all notified culture positive TB cases in 2007-2010 were obtained from National TB Registry at Taiwan CDC. A medical audit of TB case management files was performed to collect pretreatment body weight and regimens prescribed at commencement of treatment. Dosages prescribed were compared with dosages recommended. The proportion of patients with recorded pre-treatment body weight was 64.5% in 2003, which increased to 96.5% in 2007-2010 (p",

author = "Chiang, {Chen Yuan} and Yu, {Ming Chih} and Shih, {Hsiu Chen} and Yen, {Muh Yong} and Hsu, {Yu Ling} and Yang, {Shiang Lin} and Lin, {Tao Ping} and Bai, {Kuan Jen}",

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AU - Chiang, Chen Yuan

AU - Yu, Ming Chih

AU - Shih, Hsiu Chen

AU - Yen, Muh Yong

AU - Hsu, Yu Ling

AU - Yang, Shiang Lin

AU - Lin, Tao Ping

AU - Bai, Kuan Jen

PY - 2012/8/27

Y1 - 2012/8/27

N2 - Background: It was reported that 35.5% of tuberculosis (TB) cases reported in 2003 in Taipei City had no recorded pre-treatment body weight and that among those who had, inconsistent dosing of anti-TB drugs was frequent. Taiwan Centers for Disease Control (CDC) have taken actions to strengthen dosing of anti-TB drugs among general practitioners. Prescribing practices of anti-TB drugs in Taipei City in 2007-2010 were investigated to assess whether interventions on dosing were effective. Methodology/Principal Findings: Lists of all notified culture positive TB cases in 2007-2010 were obtained from National TB Registry at Taiwan CDC. A medical audit of TB case management files was performed to collect pretreatment body weight and regimens prescribed at commencement of treatment. Dosages prescribed were compared with dosages recommended. The proportion of patients with recorded pre-treatment body weight was 64.5% in 2003, which increased to 96.5% in 2007-2010 (p

AB - Background: It was reported that 35.5% of tuberculosis (TB) cases reported in 2003 in Taipei City had no recorded pre-treatment body weight and that among those who had, inconsistent dosing of anti-TB drugs was frequent. Taiwan Centers for Disease Control (CDC) have taken actions to strengthen dosing of anti-TB drugs among general practitioners. Prescribing practices of anti-TB drugs in Taipei City in 2007-2010 were investigated to assess whether interventions on dosing were effective. Methodology/Principal Findings: Lists of all notified culture positive TB cases in 2007-2010 were obtained from National TB Registry at Taiwan CDC. A medical audit of TB case management files was performed to collect pretreatment body weight and regimens prescribed at commencement of treatment. Dosages prescribed were compared with dosages recommended. The proportion of patients with recorded pre-treatment body weight was 64.5% in 2003, which increased to 96.5% in 2007-2010 (p

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Improved consistency in dosing anti-tuberculosis drugs in Taipei, Taiwan

Abstract

ASJC Scopus subject areas

UN SDGs

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