Surface oxide film on cardiovascular devices could be one of the most critical factors that determine the degree of thrombosis. Previous studies have shown that metallic wire passivated with amorphous oxide film provides excellent corrosion and scratch resistance. Investigation was undertaken to see whether this oxide film, with its unique electrochemical properties, could reduce the development of thrombosis. Results show that amorphous oxide has higher value of time constant, lower open-circuit potential, and lower degree of thrombosis. These distinguished characteristics prove amorphous oxide to be the best candidate for the cardiovascular devices. Amorphous oxide film could be a potential solution to the thrombogenic problem of cardiovascular devices.

Original languageEnglish
Pages (from-to)1320-1328
Number of pages9
JournalJournal of Biomedical Materials Research - Part A
Issue number4
Publication statusPublished - Dec 15 2003


  • Amorphous oxide
  • Open-circuit potential
  • Surface oxide
  • Thrombosis
  • Time constant

ASJC Scopus subject areas

  • Ceramics and Composites
  • Metals and Alloys
  • Biomedical Engineering
  • Biomaterials


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